Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN1A | P35498 | 1/20 | 0.48 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.48 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.48 |
| ▸ | USP30 | Q70CQ3 | 3/20 | 0.47 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.46 |
| ▸ | BACE1 | P56817 | 4/20 | 0.45 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.45 |
| ▸ | MCL1 | Q07820 | 11/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29548644 | 1.00 | SCN1A (0.48) | SCN1ASCN2ASCN3AUSP30UCHL1 | |
| SCHEMBL29548088 | 0.91 | USP30 (0.46) | SCN1ASCN2ASCN3AUSP30UCHL1 | |
| SCHEMBL29548169 | 0.90 | BACE1 (0.44) | SCN1ASCN2ASCN3AUSP30UCHL1 | |
| SCHEMBL29548231 | 0.90 | BACE1 (0.40) | SCN1ASCN2ASCN3AUSP30UCHL1 | |
| SCHEMBL29548713 | 0.89 | UCHL1 (0.41) | USP30UCHL1BACE1MCL1 | |
| SCHEMBL29548594 | 0.89 | NR1H2 (0.43) | SCN1ASCN2ASCN3AUSP30UCHL1 | |
| SCHEMBL29548383 | 0.88 | HTRA1 (0.40) | SCN1ASCN2ASCN3AUSP30UCHL1 | |
| SCHEMBL29548188 | 0.87 | SCN1A (0.50) | SCN1ASCN2ASCN3AUCHL1MCL1 | |
| SCHEMBL29548774 | 0.87 | USP30 (0.45) | SCN1ASCN2ASCN3AUSP30UCHL1 | |
| SCHEMBL29548221 | 0.87 | UCHL1 (0.47) | UCHL1BACE1BACE2MCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230416199-A1 | INHIBITORS OF AMINO ACID TRANSPORT | ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI (US) | 2023-12-28 | — | — | US | disclosed |
| WO-2022087630-A1 | INHIBITORS OF AMINO ACID TRANSPORT | ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI (US) | 2022-04-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230416199-A1 | INHIBITORS OF AMINO ACID TRANSPORT | SLC1A5, SLC7A1, SLC7A5 | SCN1A 1867/4885SCN2A 1344/4885SCN3A 2281/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.