Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTRA1 | Q92743 | 1/20 | 0.40 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.40 |
| ▸ | CHRNA7 | P36544 | 3/20 | 0.39 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.39 |
| ▸ | HTR3B | O95264 | 1/20 | 0.39 |
| ▸ | HTR3A | P46098 | 1/20 | 0.39 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.39 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.37 |
| ▸ | BACE1 | P56817 | 4/20 | 0.36 |
| ▸ | BACE2 | Q9Y5Z0 | 2/20 | 0.36 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.36 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.35 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.35 |
| ▸ | SCN1A | P35498 | 1/20 | 0.35 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.35 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29548644 | 0.88 | SCN1A (0.48) | UCHL1MCL1BACE1BACE2USP30 | |
| SCHEMBL29548397 | 0.88 | SCN1A (0.48) | UCHL1MCL1BACE1BACE2USP30 | |
| SCHEMBL29548713 | 0.86 | UCHL1 (0.41) | HTRA1UCHL1CHRNA7HTR3EHTR3B | |
| SCHEMBL9006283 | 0.83 | MMP2 (0.46) | HTRA1UCHL1CHRNA7HTR3EHTR3B | |
| SCHEMBL29548767 | 0.82 | NPC1 (0.44) | UCHL1USP30 | |
| SCHEMBL29549024 | 0.82 | MCL1 (0.48) | CHRNA7MCL1PRMT5 | |
| SCHEMBL29548231 | 0.82 | BACE1 (0.40) | UCHL1MCL1BACE1BACE2USP30 | |
| SCHEMBL29548088 | 0.81 | USP30 (0.46) | UCHL1MCL1BACE1BACE2USP30 | |
| SCHEMBL29548169 | 0.81 | BACE1 (0.44) | UCHL1MCL1BACE1BACE2USP30 | |
| SCHEMBL20705029 | 0.80 | CHRNA7 (0.44) | HTRA1UCHL1CHRNA7HTR3EHTR3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230416199-A1 | INHIBITORS OF AMINO ACID TRANSPORT | ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI (US) | 2023-12-28 | — | — | US | disclosed |
| WO-2022087630-A1 | INHIBITORS OF AMINO ACID TRANSPORT | ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI (US) | 2022-04-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230416199-A1 | INHIBITORS OF AMINO ACID TRANSPORT | SLC1A5, SLC7A1, SLC7A5 | HTRA1 2746/4885UCHL1 3033/4885CHRNA7 4778/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.