Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 3/20 | 0.35 |
| ▸ | CYP4A11 | Q02928 | 3/20 | 0.35 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.34 |
| ▸ | RET | P07949 | 3/20 | 0.32 |
| ▸ | CAMKK1 | Q8N5S9 | 1/20 | 0.32 |
| ▸ | CAMKK2 | Q96RR4 | 1/20 | 0.32 |
| ▸ | RXRA | P19793 | 1/20 | 0.32 |
| ▸ | RXRB | P28702 | 1/20 | 0.32 |
| ▸ | RXRG | P48443 | 1/20 | 0.32 |
| ▸ | IDH1 | O75874 | 1/20 | 0.30 |
| ▸ | ATR | Q13535 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29548233 | 0.84 | CAMKK1 (0.36) | CD274RETCAMKK1CAMKK2 | |
| SCHEMBL29548387 | 0.82 | CYP4F2 (0.41) | CYP4F2CYP4A11ATR | |
| SCHEMBL26114225 | 0.80 | CD274 (0.42) | CYP4F2CYP4A11CD274RETIDH1 | |
| SCHEMBL29548356 | 0.73 | PIK3CA (0.32) | CAMKK1CAMKK2 | |
| SCHEMBL31510673 | 0.71 | CD274 (0.39) | CYP4F2CYP4A11CD274RETIDH1 | |
| SCHEMBL27380210 | 0.69 | CD274 (0.37) | CYP4F2CYP4A11CD274RETIDH1 | |
| SCHEMBL29548522 | 0.69 | ALDH1A1 (0.33) | CAMKK1CAMKK2 | |
| SCHEMBL27277685 | 0.68 | CD274 (0.47) | CYP4F2CYP4A11CD274IDH1 | |
| SCHEMBL15465167 | 0.66 | CD274 (0.40) | CYP4F2CYP4A11CD274IDH1 | |
| SCHEMBL15464745 | 0.66 | CD274 (0.40) | CYP4F2CYP4A11CD274IDH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022070288-A1 | NITROGEN-CONTAINING BICYCLIC COMPOUND | 旭化成ファーマ株式会社 | 2022-04-07 | — | — | WO | disclosed |