Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 6/20 | 0.32 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.31 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | ESR1 | P03372 | 1/20 | 0.30 |
| ▸ | CAMKK1 | Q8N5S9 | 1/20 | 0.30 |
| ▸ | CAMKK2 | Q96RR4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29548852 | 0.81 | CAMKK1 (0.34) | PDE10ACAMKK1CAMKK2 | |
| SCHEMBL29548217 | 0.80 | ALDH1A1 (0.40) | ALDH1A1L3MBTL1PDE10ATSHRNPSR1 | |
| SCHEMBL29549126 | 0.79 | PDE10A (0.34) | PDE10ACAMKK1CAMKK2 | |
| SCHEMBL29548244 | 0.78 | ALDH1A1 (0.34) | ALDH1A1L3MBTL1PDE10ATSHRNPSR1 | |
| SCHEMBL29548569 | 0.78 | GRIN1 (0.50) | ALDH1A1PDE10AGRIN1GRIN2BNPSR1 | |
| SCHEMBL29548356 | 0.77 | PIK3CA (0.32) | CAMKK1CAMKK2 | |
| SCHEMBL29548173 | 0.73 | PDE10A (0.34) | PDE10A | |
| SCHEMBL29548866 | 0.73 | — | — | |
| SCHEMBL5363819 | 0.72 | TYR (0.39) | ALDH1A1GRIN1GRIN2BMAPTMAPK1 | |
| SCHEMBL29548251 | 0.71 | JAK2 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022070288-A1 | NITROGEN-CONTAINING BICYCLIC COMPOUND | 旭化成ファーマ株式会社 | 2022-04-07 | — | — | WO | disclosed |