Known targets — ChEMBL curated mechanism
ADRB1CDK4CDK6CHRM2CHRM3DPP4DRD2DRD3DRD4EGFRHRH1HTR1BHTR1DHTR1FHTR2AHTR2CHTR4SLC6A2SLC6A4
The experimentally established mechanism targets of Succinic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC25B | P30305 | 2/20 | 0.59 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.56 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.56 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.56 |
| ▸ | CNR2 | P34972 | 3/20 | 0.55 |
| ▸ | BCL2 | P10415 | 1/20 | 0.51 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.51 |
| ▸ | BAD | Q92934 | 1/20 | 0.51 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.50 |
| ▸ | PLK1 | P53350 | 1/20 | 0.50 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.48 |
| ▸ | GCGR | P47871 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL547632 | 0.91 | CDC25B (0.69) | CDC25BNR4A2NR4A1NR4A3CNR2 | |
| SCHEMBL29522736 | 0.91 | CDC25B (0.69) | CDC25BNR4A2NR4A1NR4A3CNR2 | |
| Naphthalene SCHEMBL11467392 | 0.89 | CDC25B (0.67) | CDC25BNR4A2NR4A1NR4A3CNR2 | |
| Benzil SCHEMBL10791220 | 0.86 | CDC25B (0.62) | CDC25BNR4A2NR4A1NR4A3CNR2 | |
| Sulfuric Acid SCHEMBL10833751 | 0.83 | CDC25B (0.59) | CDC25BNR4A2NR4A1NR4A3CNR2 | |
| SCHEMBL29387947 | 0.82 | ALDH1A1 (0.63) | CDC25BNR4A2NR4A1NR4A3CNR2 | |
| SCHEMBL818033 | 0.82 | ALDH1A1 (0.63) | CDC25BNR4A2NR4A1NR4A3CNR2 | |
| SCHEMBL7189887 | 0.82 | CDC25B (0.68) | CDC25BNR4A2NR4A1NR4A3CNR2 | |
| SCHEMBL717723 | 0.81 | AKR1C3 (0.64) | CDC25BNR4A2NR4A1NR4A3MAPT | |
| SCHEMBL7905161 | 0.81 | CDC25B (0.56) | CDC25BNR4A2NR4A1NR4A3CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022071387-A1 | POLARIZING FILM, OPTICAL FILM, AND IMAGE DISPLAY DEVICE | 日東電工株式会社 | 2022-04-07 | — | — | WO | disclosed |