SCHEMBL818033

SCHEMBL818033

O=C(O)CCC(=O)c1cccc2ccccc12

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.63
HPGD P15428 4/20 0.63
KDM4E B2RXH2 4/20 0.63
MAPT P10636 4/20 0.63
POLB P06746 3/20 0.63
KMT2A Q03164 3/20 0.63
TDP1 Q9NUW8 3/20 0.63
CYP1A2 P05177 2/20 0.63
CYP2D6 P10635 2/20 0.63
HSD17B10 Q99714 2/20 0.63
MEN1 O00255 2/20 0.63
GMNN O75496 2/20 0.63
LMNA P02545 2/20 0.63
MAPK1 P28482 2/20 0.63
BLM P54132 2/20 0.63
PMP22 Q01453 2/20 0.63
NPSR1 Q6W5P4 2/20 0.63
CMKLR1 Q99788 2/20 0.63
GLA P06280 1/20 0.63
TP53 P04637 1/20 0.63

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29387947 1.00 ALDH1A1 (0.63) ALDH1A1HPGDKDM4EMAPTPOLB
SCHEMBL7966051 0.90 ALDH1A1 (0.65) ALDH1A1HPGDKDM4EMAPTPOLB
SCHEMBL3381314 0.89 ALDH1A1 (0.59) ALDH1A1HPGDKDM4EMAPTPOLB
SCHEMBL3382572 0.88 MAPT (0.58) ALDH1A1HPGDKDM4EMAPTPOLB
SCHEMBL27819105 0.88 MAPT (0.58) ALDH1A1HPGDKDM4EMAPTPOLB
SCHEMBL8536609 0.84 ALDH1A1 (0.66) ALDH1A1HPGDKDM4EMAPTPOLB
SCHEMBL10416279 0.83 ALDH1A1 (0.65) ALDH1A1HPGDKDM4EMAPTPOLB
SCHEMBL3371176 0.83 PTPN1 (0.65) ALDH1A1HPGDKDM4EMAPTPOLB
SCHEMBL1716864 0.83 ALDH1A1 (0.70) ALDH1A1HPGDKDM4EMAPTPOLB
SCHEMBL29875679 0.83 ALDH1A1 (0.70) ALDH1A1HPGDKDM4EMAPTPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-63139172-A None JP disclosed
CN-114213435-B Preparation and application of bis- (10-deoxydihydroartemisinin) -phloroglucinol derivative 云白药征武科技(上海)有限公司 2023-03-21 CN disclosed
CN-114213435-A Preparation and application of bis- (10-deoxydihydroartemisinin) -phloroglucinol derivative 云白药征武科技(上海)有限公司 2022-03-22 CN disclosed
US-9580571-B2 Aromatic acylation with cyclic anhydride for plasticizer production EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2017-02-28 US disclosed
US-9512296-B2 Aromatic acylation with cyclic anhydride for plasticizer production EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2016-12-06 US disclosed
US-20140100384-A1 AROMATIC ACYLATION WITH CYCLIC ANHYDRIDE FOR PLASTICIZER PRODUCTION EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2014-04-10 US disclosed
US-20140100383-A1 AROMATIC ACYLATION WITH CYCLIC ANHYDRIDE FOR PLASTICIZER PRODUCTION EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2014-04-10 US disclosed
US-8604114-B2 Aromatic acylation with cyclic anhydride for plasticizer production EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2013-12-10 US disclosed
US-20110160371-A1 AROMATIC ACYLATION WITH CYCLIC ANHYDRIDE FOR PLASTICIZER PRODUCTION EXXONMOBILE RESEARCH AND ENGINEERING COMPANY (US) 2011-06-30 US disclosed
US-7691889-B2 Antimycobacterial compounds LUPIN LIMITED (IN) 2010-04-06 US disclosed
US-5552409-A PHYTOPATHOGENIC, RICE ROHM AND HAAS COMPANY (US) 1996-09-03 US disclosed
US-5443753-A Reaction products of lyotropic liquid crystal salt complexes ELLIOTT STANLEY B (US) 1995-08-22 US disclosed
US-5354499-A Reaction products of lyotropic liquid crystal salt complexes ELLIOTT STANLEY B (US) 1994-10-11 US disclosed
US-5354496-A Lyotropic liquid crystal salt/inorganic compound complexation products ELLIOTT STANLEY B (US) 1994-10-11 US disclosed
EP-0478195-A1 Dihydropyridazinones, pyridazinones and related compounds as fungicides ROHM AND HAAS COMPANY (US) 1992-04-01 EP disclosed
US-5082588-A Hygrometers ELLIOTT STANLEY B (US) 1992-01-21 US disclosed
US-4975249-A Optical and capacitance type, phase transition, humidity-responsive devices ELLIOTT STANLEY B (US) 1990-12-04 US disclosed
JP-S63139172-A 4,5-DIHYDRO-6-(6-SUBSTITUTED-2-NAPHTHYL)-3(2H)-PYRIDAZINONE DERIVATIVE MORISHITA SEIYAKU KK 1988-06-10 JP disclosed
US-4435329-A ANTIHYPERTENSIVE AGENTS AMERICAN CYANAMID COMPANY (US) 1984-03-06 US disclosed
US-4374249-A HYPOTENSIVE AGENTS AMERICAN CYANAMID COMPANY (US) 1983-02-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110160371-A1 AROMATIC ACYLATION WITH CYCLIC ANHYDRIDE FOR PLASTICIZER PRODUCTION ACAD11, ACOT7, ACOX3 ALDH1A1 312/4885HPGD 523/4885KDM4E 178/4885
US-20140100383-A1 AROMATIC ACYLATION WITH CYCLIC ANHYDRIDE FOR PLASTICIZER PRODUCTION ACAD11, ACOT7, ACOX3 ALDH1A1 312/4885HPGD 523/4885KDM4E 178/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.