SCHEMBL29549243

SCHEMBL29549243

C=C(C)C(=O)OCCNC(=O)Oc1ccc2ccccc2c1-c1c(OC(=O)Nc2cccc3ccccc23)ccc2ccccc12

nearest known ligand 0.54

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.46
HPGD P15428 3/20 0.46
NCEH1 Q6PIU2 2/20 0.43
EPHX1 P07099 1/20 0.41
HTR1A P08908 1/20 0.41
DRD2 P14416 1/20 0.41
TRPV1 Q8NER1 1/20 0.40
KDM4E B2RXH2 3/20 0.40
MAPT P10636 2/20 0.39
ALOX12 P18054 1/20 0.39
MEN1 O00255 2/20 0.39
KMT2A Q03164 2/20 0.39
CA12 O43570 1/20 0.39
CA4 P22748 1/20 0.39
CA7 P43166 1/20 0.39
CA9 Q16790 1/20 0.39
CA14 Q9ULX7 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19712936 1.00 ALDH1A1 (0.46) ALDH1A1HPGDNCEH1EPHX1HTR1A
SCHEMBL13380544 0.92 NCEH1 (0.49) ALDH1A1HPGDNCEH1KDM4EMAPT
SCHEMBL29549143 0.91 NCEH1 (0.40) ALDH1A1HPGDNCEH1HTR1ADRD2
SCHEMBL19712916 0.91 NCEH1 (0.40) ALDH1A1HPGDNCEH1HTR1ADRD2
SCHEMBL19712905 0.86 NCEH1 (0.60) ALDH1A1HPGDNCEH1KDM4E
SCHEMBL29549149 0.85 ALDH1A1 (0.45) ALDH1A1HPGDNCEH1EPHX1HTR1A
SCHEMBL29549156 0.85 NCEH1 (0.43) ALDH1A1HPGDNCEH1DRD2KDM4E
SCHEMBL19712930 0.85 NCEH1 (0.43) ALDH1A1HPGDNCEH1DRD2KDM4E
SCHEMBL19712902 0.85 ALDH1A1 (0.45) ALDH1A1HPGDNCEH1EPHX1HTR1A
SCHEMBL19712894 0.84 NCEH1 (0.55) NCEH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3622512-B1 FILM STRUCTURE COMPRISING A PHOTOPOLYMER COATING FOR HOLOGRAPHIC EXPOSURE AND A LACQUER LAYER WITH HIGH RESISTANCE COVESTRO INTELLECTUAL PROPERTY GMBH & CO KG (DE) 2022-04-27 EP disclosed