SCHEMBL19712902

SCHEMBL19712902

C=CC(=O)OCCNC(=O)Oc1ccc2ccccc2c1-c1c(OC(=O)Nc2cccc3ccccc23)ccc2ccccc12

nearest known ligand 0.53

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.45
HPGD P15428 2/20 0.45
NCEH1 Q6PIU2 2/20 0.41
TRPV1 Q8NER1 1/20 0.41
HTR1A P08908 1/20 0.39
DRD2 P14416 1/20 0.39
EPHX1 P07099 1/20 0.39
MAPT P10636 3/20 0.39
MEN1 O00255 3/20 0.38
KMT2A Q03164 3/20 0.38
ALOX12 P18054 1/20 0.38
LMNA P02545 1/20 0.38
KDM4E B2RXH2 4/20 0.38
GSK3B P49841 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29549149 1.00 ALDH1A1 (0.45) ALDH1A1HPGDNCEH1TRPV1HTR1A
SCHEMBL17825875 0.92 NCEH1 (0.47) ALDH1A1HPGDNCEH1DRD2MAPT
SCHEMBL29549723 0.90 NCEH1 (0.40) ALDH1A1HPGDNCEH1TRPV1HTR1A
SCHEMBL19712953 0.90 NCEH1 (0.40) ALDH1A1HPGDNCEH1TRPV1HTR1A
SCHEMBL20484007 0.88 NCEH1 (0.44) ALDH1A1HPGDNCEH1DRD2MAPT
SCHEMBL29549243 0.85 ALDH1A1 (0.46) ALDH1A1HPGDNCEH1TRPV1HTR1A
SCHEMBL19712936 0.85 ALDH1A1 (0.46) ALDH1A1HPGDNCEH1TRPV1HTR1A
SCHEMBL29549028 0.85 NCEH1 (0.60) HPGDNCEH1
SCHEMBL19712926 0.85 NCEH1 (0.60) HPGDNCEH1
SCHEMBL29549156 0.84 NCEH1 (0.43) ALDH1A1HPGDNCEH1DRD2MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11267943-B2 Film structure containing a photopolymer layer for holographic exposure and a coating layer of high resistance COVESTRO DEUTSCHLAND AG (DE) 2022-03-08 US disclosed
CN-110603589-B Holographic media comprising a holographically exposed photopolymer layer and a high tolerance coating layer 科思创德国股份有限公司 2021-11-16 CN disclosed
US-20210292505-A1 FILM STRUCTURE CONTAINING A PHOTOPOLYMER LAYER FOR HOLOGRAPHIC EXPOSURE AND A COATING LAYER OF HIGH RESISTANCE COVESTRO DEUTSCHLAND AG (DE) 2021-09-23 US disclosed
CN-110582808-B Film structure comprising a photopolymer layer and a high resistance coating layer for holographic exposure 科思创德国股份有限公司 2021-08-27 CN disclosed
US-20200166888-A1 HOLOGRAPHIC MEDIUM CONTAINING A PHOTOPOLYMER LAYER FOR HOLOGRAPHIC EXPOSURE AND A HIGHLY RESISTANT COATING LAYER COVESTRO DEUTSCHLAND AG (DE) 2020-05-28 US disclosed
CN-110603589-A Holographic media comprising a photopolymer layer and a high tolerance coating layer for holographic exposure 科思创德国股份有限公司 2019-12-20 CN disclosed
CN-110582808-A Film structure comprising a photopolymer layer and a high resistance coating layer for holographic exposure 科思创德国股份有限公司 2019-12-17 CN disclosed
US-10241402-B2 Naphthyl acrylates as writing monomers for photopolymers COVESTRO DEUTSCHLAND AG (DE) 2019-03-26 US disclosed
US-20170363957-A1 NAPHTHYL ACRYLATES AS WRITING MONOMERS FOR PHOTOPOLYMERS COVESTRO DEUTSCHLAND AG (DE) 2017-12-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170363957-A1 NAPHTHYL ACRYLATES AS WRITING MONOMERS FOR PHOTOPOLYMERS NEFM, ACR, DIAPH1 ALDH1A1 1558/4885HPGD 18/4885NCEH1 4259/4885
US-10241402-B2 Naphthyl acrylates as writing monomers for photopolymers NEFM, ACR, DIAPH1 ALDH1A1 1558/4885HPGD 18/4885NCEH1 4259/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.