Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIN1 | Q13526 | 8/20 | 0.51 |
| ▸ | LCK | P06239 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22807430 | 1.00 | PIN1 (0.51) | PIN1LCKMAPTKMT2ATSHR | |
| SCHEMBL22807432 | 0.85 | PIN1 (0.51) | PIN1LCKMAPTKMT2ASMN1; SMN2 | |
| SCHEMBL29549204 | 0.85 | PIN1 (0.51) | PIN1LCKMAPTKMT2ASMN1; SMN2 | |
| SCHEMBL21846996 | 0.79 | PIN1 (0.59) | PIN1MAPTKMT2ASMN1; SMN2MEN1 | |
| SCHEMBL30939734 | 0.79 | PIN1 (0.59) | PIN1MAPTKMT2ASMN1; SMN2MEN1 | |
| SCHEMBL31684796 | 0.78 | LCK (0.46) | LCKMAPTKMT2AALDH1A1 | |
| SCHEMBL6193458 | 0.77 | PIN1 (0.54) | PIN1LCKMAPTKMT2ASMN1; SMN2 | |
| SCHEMBL22807418 | 0.76 | BRD4 (0.71) | — | |
| SCHEMBL1080985 | 0.75 | JAK3 (0.47) | LCKSMN1; SMN2ALDH1A1 | |
| SCHEMBL27154560 | 0.75 | KMT2A (0.46) | LCKMAPTKMT2ATSHRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4617261-A1 | 2,4,5-TRISUBSTITUTED PYRIMIDINE COMPOUND, PREPARATION METHOD THEREFOR, AND USE THEREOF | Wenzhou Medical University (CN) | 2025-09-17 | — | — | EP | disclosed |
| CN-115894381-B | 2,4, 5-Trisubstituted pyrimidine compound and preparation method and application thereof | 温州医科大学 | 2024-10-18 | — | — | CN | disclosed |
| EP-3986411-A1 | SMALL MOLECULE INHIBITORS OF SRC TYROSINE KINASE | Dana-Farber Cancer Institute, Inc. (US) | 2022-04-27 | — | — | EP | disclosed |