Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN2A | Q99250 | 2/20 | 0.54 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.54 |
| ▸ | HIPK4 | Q8NE63 | 1/20 | 0.54 |
| ▸ | APEX1 | P27695 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 4/20 | 0.44 |
| ▸ | RECQL | P46063 | 2/20 | 0.44 |
| ▸ | CASP6 | P55212 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.44 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30268547 | 0.87 | ALDH1A1 (0.54) | SCN2APIM3HIPK4APEX1ALDH1A1 | |
| SCHEMBL30268562 | 0.81 | ALDH1A1 (0.48) | SCN2APIM3HIPK4APEX1ALDH1A1 | |
| SCHEMBL7820971 | 0.81 | DNMT3A (0.55) | SCN2APIM3HIPK4APEX1ALDH1A1 | |
| SCHEMBL29549970 | 0.81 | SCN2A (0.54) | SCN2APIM3HIPK4APEX1ALDH1A1 | |
| SCHEMBL30268504 | 0.80 | ALDH1A1 (0.47) | SCN2APIM3HIPK4APEX1ALDH1A1 | |
| N-Phthaloylanthranilic Acid SCHEMBL481284 | 0.80 | APEX1 (0.71) | SCN2APIM3HIPK4APEX1ALDH1A1 | |
| N-Phthaloylanthranilic Acid SCHEMBL29549628 | 0.80 | APEX1 (0.71) | SCN2APIM3HIPK4APEX1ALDH1A1 | |
| SCHEMBL30268430 | 0.78 | ALDH1A1 (0.45) | SCN2APIM3HIPK4APEX1ALDH1A1 | |
| SCHEMBL30267983 | 0.78 | ALDH1A1 (0.48) | SCN2APIM3HIPK4APEX1ALDH1A1 | |
| SCHEMBL17104364 | 0.78 | SMN1; SMN2 (0.47) | GAAPOLBCASP6L3MBTL1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110452152-B | 1, 3-dioxo isoindoline benzamide compound and application thereof | 中国医学科学院药物研究所 | 2022-05-20 | — | — | CN | disclosed |