Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNMT3A | Q9Y6K1 | 1/20 | 0.55 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.54 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.54 |
| ▸ | HIPK4 | Q8NE63 | 1/20 | 0.54 |
| ▸ | APEX1 | P27695 | 1/20 | 0.54 |
| ▸ | DNM2 | P50570 | 1/20 | 0.53 |
| ▸ | MYC | P01106 | 2/20 | 0.53 |
| ▸ | CA2 | P00918 | 3/20 | 0.49 |
| ▸ | CA9 | Q16790 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | CASP1 | P29466 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | MITF | O75030 | 1/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8654996 | 0.89 | ALDH1A1 (0.55) | DNMT3ASCN2APIM3HIPK4APEX1 | |
| SCHEMBL30268190 | 0.87 | DNM2 (0.48) | DNMT3ASCN2APIM3HIPK4APEX1 | |
| SCHEMBL29549970 | 0.81 | SCN2A (0.54) | SCN2APIM3HIPK4APEX1CA2 | |
| SCHEMBL29549481 | 0.81 | SCN2A (0.54) | SCN2APIM3HIPK4APEX1DNM2 | |
| N-Phthaloylanthranilic Acid SCHEMBL29549628 | 0.80 | APEX1 (0.71) | SCN2APIM3HIPK4APEX1MYC | |
| N-Phthaloylanthranilic Acid SCHEMBL481284 | 0.80 | APEX1 (0.71) | SCN2APIM3HIPK4APEX1MYC | |
| SCHEMBL30268562 | 0.79 | ALDH1A1 (0.48) | DNMT3ASCN2APIM3HIPK4APEX1 | |
| SCHEMBL30268430 | 0.78 | ALDH1A1 (0.45) | DNMT3ASCN2APIM3HIPK4APEX1 | |
| SCHEMBL6708180 | 0.78 | MEN1 (0.56) | KMT2AMEN1CYP3A4NFKB1PMP22 | |
| SCHEMBL29550110 | 0.78 | SCN2A (0.50) | SCN2APIM3HIPK4APEX1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1091958-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2001-04-18 | — | — | EP | disclosed |
| WO-2000001692-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2000-01-13 | — | — | WO | disclosed |