Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRAF | P15056 | 2/20 | 0.50 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.50 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.50 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.50 |
| ▸ | CALM1 | P0DP23 | 2/20 | 0.47 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.46 |
| ▸ | DYRK1A | Q13627 | 3/20 | 0.45 |
| ▸ | CLK4 | Q9HAZ1 | 3/20 | 0.45 |
| ▸ | VCP | P55072 | 1/20 | 0.45 |
| ▸ | FYN | P06241 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | AURKA | O14965 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22533767 | 1.00 | BRAF (0.50) | BRAFADORA3ADORA2AADORA1CALM1 | |
| SCHEMBL31456192 | 0.88 | ADORA2A (0.57) | BRAFADORA3ADORA2AADORA1DYRK1A | |
| SCHEMBL31456247 | 0.88 | ADORA3 (0.57) | ADORA3ADORA2AADORA1DYRK1ACLK4 | |
| Hydrochloric Acid SCHEMBL30197739 | 0.87 | TP53 (0.49) | BRAFADORA3ADORA2AADORA1DYRK1A | |
| SCHEMBL31456205 | 0.86 | ADORA1 (0.62) | ADORA3ADORA2AADORA1DYRK1ACLK4 | |
| SCHEMBL29379328 | 0.85 | PTGDR (0.56) | BRAFADORA3ADORA2AADORA1DYRK1A | |
| SCHEMBL430891 | 0.85 | PTGDR (0.56) | BRAFADORA3ADORA2AADORA1DYRK1A | |
| SCHEMBL31456150 | 0.85 | HPGD (0.48) | BRAFADORA3ADORA2AADORA1DYRK1A | |
| Hydrochloric Acid SCHEMBL29549744 | 0.84 | PTGDR (0.55) | BRAFADORA3ADORA2AADORA1DYRK1A | |
| Hydrochloric Acid SCHEMBL19668265 | 0.84 | PTGDR (0.55) | BRAFADORA3ADORA2AADORA1DYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3952849-A2 | COMPOSITIONS AND METHODS FOR INCREASING MUSCLE MASS AND OXIDATIVE METABOLISM | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2022-02-16 | — | — | EP | disclosed |