Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR | Q13258 | 2/20 | 0.56 |
| ▸ | CLK4 | Q9HAZ1 | 3/20 | 0.55 |
| ▸ | BRAF | P15056 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.48 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.48 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.47 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.47 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.47 |
| ▸ | PDE5A | O76074 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29379328 | 1.00 | PTGDR (0.56) | PTGDRCLK4BRAFALDH1A1DYRK1A | |
| Hydrochloric Acid SCHEMBL29549744 | 0.99 | PTGDR (0.55) | PTGDRCLK4BRAFALDH1A1DYRK1A | |
| Hydrochloric Acid SCHEMBL19668265 | 0.99 | PTGDR (0.55) | PTGDRCLK4BRAFALDH1A1DYRK1A | |
| SCHEMBL24454337 | 0.91 | DYRK1A (0.51) | PTGDRCLK4ALDH1A1DYRK1APDE5A | |
| SCHEMBL22541070 | 0.90 | ALDH1A1 (0.49) | PTGDRCLK4BRAFALDH1A1DYRK1A | |
| SCHEMBL24454264 | 0.90 | CLK4 (0.47) | PTGDRCLK4BRAFALDH1A1DYRK1A | |
| SCHEMBL24454573 | 0.90 | BRAF (0.48) | PTGDRCLK4BRAFALDH1A1DYRK1A | |
| SCHEMBL22541055 | 0.90 | BRAF (0.46) | PTGDRCLK4BRAFALDH1A1DYRK1A | |
| SCHEMBL22541061 | 0.89 | CLK4 (0.46) | PTGDRCLK4BRAFALDH1A1DYRK1A | |
| SCHEMBL22533936 | 0.87 | CALM1 (0.51) | CLK4ALDH1A1DYRK1APDE5AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 541 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250154468-A1 | METHOD FOR INDUCING DEDIFFERENTIATION OF ADIPOCYTES | CITY UNIVERSITY OF HONG KONG (HK) | 2025-05-15 | — | — | US | claimed |
| US-20240240154-A1 | COLONIC ORGANOIDS AND METHODS OF MAKING AND USING SAME | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2024-07-18 | — | — | US | claimed |
| CN-118355110-A | Method for producing cartilage and bone | 默多克儿童研究所 | 2024-07-16 | — | — | CN | claimed |
| US-20240166998-A1 | METHOD FOR PRODUCING HEMATOPOIETIC CELLS FROM STEM CELLS USING VASCULAR ORGANOIDS | GALAT, Yekaterina | 2024-05-23 | — | — | US | claimed |
| EP-4326852-A1 | METHOD FOR PRODUCING HEMATOPOIETIC CELLS FROM STEM CELLS USING VASCULAR ORGANOIDS | Artec Biotech, Inc. (US) | 2024-02-28 | — | — | EP | claimed |
| US-11767515-B2 | Colonic organoids and methods of making and using same | CHILDREN'S HOSPITAL MEDICAL CENTER (US) | 2023-09-26 | — | — | US | claimed |
| EP-3914697-A1 | CHOROID PLEXUS ORGANOIDS AND METHODS FOR PRODUCTION THEREOF | United Kingdom Research and Innovation (GB) | 2021-12-01 | — | — | EP | claimed |
| CN-113631701-A | Choroid plexus organoids and methods of producing the same | 英国研究与创新组织 | 2021-11-09 | — | — | CN | claimed |
| US-20210324334-A1 | ORGANOID COMPOSITIONS FOR THE PRODUCTION OF HEMATOPOIETIC STEM CELLS AND DERIVATIVES THEREOF | CHILDREN'S HOSPITAL MEDICAL CENTER | 2021-10-21 | — | — | US | claimed |
| EP-3856765-A1 | STEM CELL-DERIVED HUMAN MICROGLIAL CELLS, METHODS OF MAKING AND METHODS OF USE | Memorial Sloan Kettering Cancer Center (US) | 2021-08-04 | — | — | EP | claimed |
| EP-2788472-A2 | METHOD OF DIRECTED DIFFERENTIATION PRODUCING CORNEAL ENDOTHELIAL CELLS, COMPOSITIONS THEREOF, AND USES THEREOF | Advanced Cell Technology, Inc. (US) | 2014-10-15 | — | — | EP | claimed |
| WO-2014143022-A1 | COMPOSITIONS AND METHODS FOR TREATING RETINAL DISEASE | TRESE MICHAEL T (US) | 2014-09-18 | — | — | WO | claimed |
| US-20140199277-A1 | Methods of Treatment of Retinal Degeneration Diseases | Sanges, Daniela (ES) | 2014-07-17 | — | — | US | claimed |
| EP-2739723-A1 | METHODS OF TREATMENT OF RETINAL DEGENERATION DISEASES | Cosma, Maria Pia (ES) | 2014-06-11 | — | — | EP | claimed |
| WO-2014018691-A1 | GENERATION OF AIRWAY AND LUNG PROGENITORS AND EPITHELIAL CELLS AND THREE-DIMENSIONAL ANTERIOR FOREGUT SPHERES | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2014-01-30 | — | — | WO | claimed |
| WO-2013086236-A2 | METHOD OF DIRECTED DIFFERENTIATION PRODUCING CORNEAL ENDOTHELIAL CELLS, COMPOSITIONS THEREOF, AND USES THEREOF | ADVANCED CELL TECHNOLOGY, INC. (US) | 2013-06-13 | — | — | WO | claimed |
| WO-2013020945-A9 | METHODS OF TREATMENT OF RETINAL DEGENERATION DISEASES | COSMA MARIA PIA (ES) | 2013-04-04 | — | — | WO | claimed |
| WO-2013020945-A1 | METHODS OF TREATMENT OF RETINAL DEGENERATION DISEASES | COSMA MARIA PIA (ES) | 2013-02-14 | — | — | WO | claimed |
| WO-2011049954-A2 | COMPOSITIONS COMPRISING WNT MODULATORS OR NEUROTOXINS FOR THE TREATMENT OF OTIC DISORDERS | OTONOMY, INC. (US) | 2011-04-28 | — | — | WO | claimed |
| WO-2008133904-A1 | METHODS AND COMPOSITIONS FOR STEM CELL SELF-RENEWAL | STOWERS INSTITUTE FOR MEDICAL RESEARCH (US) | 2008-11-06 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140199277-A1 | Methods of Treatment of Retinal Degeneration Diseases | ALDH1A2, NR2E3, RARB | PTGDR 2485/4885CLK4 3354/4885BRAF 1383/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.