Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK1 | Q15118 | 1/20 | 0.42 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.42 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.42 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.42 |
| ▸ | LCK | P06239 | 6/20 | 0.41 |
| ▸ | CHRNA7 | P36544 | 6/20 | 0.41 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | DHODH | Q02127 | 1/20 | 0.40 |
| ▸ | CARM1 | Q86X55 | 2/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6677854 | 0.92 | KDM4E (0.44) | CHRNA7KLKB1KDM4EMEN1ALDH1A1 | |
| SCHEMBL12911821 | 0.91 | CARM1 (0.41) | KLKB1KDM4EMEN1ALDH1A1MAPT | |
| SCHEMBL951281 | 0.90 | KLKB1 (0.41) | CHRNA7KLKB1DHODHCARM1 | |
| SCHEMBL6688876 | 0.89 | KCNMA1 (0.42) | KLKB1KDM4EMEN1ALDH1A1MAPT | |
| SCHEMBL6677548 | 0.89 | KDM4E (0.40) | KLKB1KDM4EMEN1ALDH1A1MAPT | |
| SCHEMBL12911572 | 0.88 | DHODH (0.39) | KLKB1KDM4EMEN1ALDH1A1MAPT | |
| SCHEMBL29393434 | 0.88 | DHODH (0.39) | KLKB1KDM4EMEN1ALDH1A1MAPT | |
| SCHEMBL1380391 | 0.88 | DHODH (0.39) | KLKB1KDM4EMEN1ALDH1A1MAPT | |
| SCHEMBL12911831 | 0.87 | CARM1 (0.43) | KLKB1KDM4EMEN1ALDH1A1MAPT | |
| SCHEMBL6713256 | 0.87 | DHODH (0.41) | KLKB1KDM4EMEN1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7754738-B2 | Pyrazole and pyrrole carboxamide insecticides | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2010-07-13 | — | — | US | disclosed |
| US-20060167060-A1 | Pyrazole and pyrrole carboxamide insecticides | E. I. DU PONT DE NEMOURS AND COMPANY | 2006-07-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060167060-A1 | Pyrazole and pyrrole carboxamide insecticides | CBR3, C1S, CBR1 | PDK1 288/4885PDK2 494/4885PDK3 214/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.