Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 1/20 | 0.41 |
| ▸ | KLKB1 | P03952 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CARM1 | Q86X55 | 2/20 | 0.39 |
| ▸ | F9 | P00740 | 2/20 | 0.39 |
| ▸ | F10 | P00742 | 2/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.38 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6677548 | 0.97 | KDM4E (0.40) | DHODHKLKB1KDM4EMEN1ALDH1A1 | |
| SCHEMBL2954964 | 0.87 | PDK1 (0.42) | DHODHKLKB1KDM4EMEN1ALDH1A1 | |
| SCHEMBL6712376 | 0.87 | MAPK14 (0.45) | KLKB1CARM1F10MAPK14TRPV1 | |
| SCHEMBL12911902 | 0.84 | DHODH (0.42) | DHODHKLKB1KDM4EMEN1ALDH1A1 | |
| SCHEMBL6677854 | 0.84 | KDM4E (0.44) | DHODHKLKB1KDM4EMEN1ALDH1A1 | |
| SCHEMBL1380391 | 0.84 | DHODH (0.39) | DHODHKLKB1KDM4EMEN1ALDH1A1 | |
| SCHEMBL29393434 | 0.84 | DHODH (0.39) | DHODHKLKB1KDM4EMEN1ALDH1A1 | |
| SCHEMBL952122 | 0.83 | KLKB1 (0.45) | DHODHKLKB1KDM4EMEN1ALDH1A1 | |
| SCHEMBL2396175 | 0.83 | TRPV1 (0.40) | KLKB1CARM1F10TRPV1 | |
| SCHEMBL12911821 | 0.82 | CARM1 (0.41) | DHODHKLKB1KDM4EMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040235959-A1 | Insecticidal diamides | E. I. DU PONT DE NEMOURS AND COMPANY | 2004-11-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040235959-A1 | Insecticidal diamides | DDT, NRDC, NOXO1 | DHODH 359/4885KLKB1 4524/4885KDM4E 2025/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.