SCHEMBL295497

SCHEMBL295497

Cc1ccc(OC(=O)c2ccc(OC(=O)c3ccc([N+](=O)[O-])cc3)cc2)cc1

nearest known ligand 0.72

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.72
PKM P14618 1/20 0.72
HGFAC Q04756 1/20 0.63
MEN1 O00255 1/20 0.61
NR1H4 Q96RI1 1/20 0.59
ACHE P22303 1/20 0.58
HSD17B10 Q99714 1/20 0.58
MAPT P10636 6/20 0.57
ALDH1A1 P00352 4/20 0.57
GAA P10253 3/20 0.55
LMNA P02545 1/20 0.55
HPGD P15428 1/20 0.55
PRSS1 P07477 1/20 0.54
ACR P10323 1/20 0.54
ALOX5 P09917 2/20 0.54
BCL9 O00512 1/20 0.53
CTNNB1 P35222 1/20 0.53
MAOA P21397 1/20 0.52
MAOB P27338 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5696807 1.00 KMT2A (0.72) KMT2APKMHGFACMEN1NR1H4
SCHEMBL2597339 1.00 KMT2A (0.72) KMT2APKMHGFACMEN1NR1H4
SCHEMBL18434657 0.92 KMT2A (0.84) KMT2APKMHGFACNR1H4MAPT
SCHEMBL542043 0.92 KMT2A (0.84) KMT2APKMHGFACNR1H4MAPT
SCHEMBL10636579 0.92 KMT2A (0.84) KMT2APKMHGFACNR1H4MAPT
SCHEMBL4951809 0.92 KMT2A (0.84) KMT2APKMHGFACNR1H4MAPT
SCHEMBL7796532 0.92 HGFAC (0.66) KMT2APKMHGFACMEN1NR1H4
SCHEMBL23918341 0.88 MAOB (0.68) KMT2APKMHGFACMEN1MAPT
SCHEMBL6986709 0.87 KMT2A (0.72) KMT2APKMHGFACMEN1NR1H4
SCHEMBL5345292 0.87 KMT2A (0.72) KMT2APKMHGFACMEN1NR1H4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210349035-A1 PATHOGEN MONITORING PLATYPUS TECHNOLOGIES, LLC 2021-11-11 US disclosed
US-10928306-B2 Functional surfaces for liquid crystal-based detection of chlorine gas WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2021-02-23 US disclosed
US-20190212254-A1 Functional Surfaces for Liquid Crystal-Based Detection of Chlorine Gas NATIONAL SCIENCE FOUNDATION 2019-07-11 US disclosed
US-20180052111-A1 SUBSTRATES, DEVICES, AND METHODS FOR QUANTITATIVE LIQUID CRYSTAL ASSAYS PLATYPUS TECHNOLOGIES, LLC 2018-02-22 US disclosed
US-9816147-B2 Liquid crystal based analyte detection PLATYPUS TECHNOLOGIES, LLC (US) 2017-11-14 US disclosed
US-9797843-B2 Substrates, devices, and methods for quantitative liquid crystal assays PLATYPUS TECHNOLOGIES, LLC (US) 2017-10-24 US disclosed
US-20170212088-A1 DETECTION OF GAS-PHASE ANALYTES USING LIQUID CRYSTALS PLATYPUS TECHNOLOGIES, LLC 2017-07-27 US disclosed
US-9575037-B2 Detection of gas-phase analytes using liquid crystals PLATYPUS TECHNOLOGIES, LLC (US) 2017-02-21 US disclosed
US-8133680-B2 affinity substrate comprises polydimethylsiloxane stamp alternately peptide-terminated or antibody terminated; WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2012-03-13 US disclosed
US-7662572-B2 Compositions and liquid crystals PLATYPUS TECHNOLOGIES, LLC. (US) 2010-02-16 US disclosed
US-7651662-B2 Rubbed substrate surfaces; activation; uniform anchoring of liquid crystals WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2010-01-26 US disclosed
US-20070099249-A1 Compositions and liquid crystals PLATYPUS TECHNOLOGIES, LLC (US) 2007-05-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070099249-A1 Compositions and liquid crystals FABP5, FABP1, SSB KMT2A 4615/4885PKM 1801/4885HGFAC 3093/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.