Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.72 |
| ▸ | PKM | P14618 | 1/20 | 0.72 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.71 |
| ▸ | HGFAC | Q04756 | 1/20 | 0.63 |
| ▸ | MAOB | P27338 | 1/20 | 0.62 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 5/20 | 0.57 |
| ▸ | GAA | P10253 | 3/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | BCL9 | O00512 | 1/20 | 0.53 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.53 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10636579 | 0.92 | KMT2A (0.84) | KMT2APKMHGFACNR1H4MAPT | |
| SCHEMBL4951809 | 0.92 | KMT2A (0.84) | KMT2APKMHGFACNR1H4MAPT | |
| SCHEMBL542043 | 0.92 | KMT2A (0.84) | KMT2APKMHGFACNR1H4MAPT | |
| SCHEMBL18434657 | 0.92 | KMT2A (0.84) | KMT2APKMHGFACNR1H4MAPT | |
| SCHEMBL5696807 | 0.87 | KMT2A (0.72) | KMT2APKMHGFACMAOBNR1H4 | |
| SCHEMBL2597339 | 0.87 | KMT2A (0.72) | KMT2APKMHGFACMAOBNR1H4 | |
| SCHEMBL5345292 | 0.87 | KMT2A (0.72) | KMT2APKMMAPK1HGFACMAOB | |
| SCHEMBL295497 | 0.87 | KMT2A (0.72) | KMT2APKMHGFACMAOBNR1H4 | |
| SCHEMBL12489991 | 0.87 | PKM (0.77) | KMT2APKMMAPK1HGFACNR1H4 | |
| SCHEMBL16375430 | 0.87 | KMT2A (0.77) | KMT2APKMMAPK1HGFACNR1H4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0934938-B1 | SUBSTITUTED BENZOYLAMINOTHIAZOLE DERIVATIVES AND DRUGS CONTAINING THE SAME | ZERIA PHARM CO LTD (JP) | 2003-01-15 | — | — | EP | disclosed |
| CN-1072652-C | Substd. benzoylaminothiazole derivatives and drugs containing same | ZERIA PHARM CO LTD (JP) | 2001-10-10 | — | — | CN | disclosed |
| US-6121301-A | ADMINISTERING TO PREVENT OR TREAT GASTROINTESTINAL DYSMOTILITY; COMPOUNDS SUCH AS 2-((N-(3-CYANOBENZOYL)AMINO)-4-((3-DIISOPROPYLAMINOPROPYL)AMINOCARBONYL)-1,3-THIAZOLE | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 2000-09-19 | — | — | US | disclosed |
| CN-1234028-A | Substd. benzoylaminothiazole derivatives and drugs containing same | ZERIA PHARM CO LTD (JP) | 1999-11-03 | — | — | CN | disclosed |
| EP-0934938-A1 | SUBSTITUTED BENZOYLAMINOTHIAZOLE DERIVATIVES AND DRUGS CONTAINING THE SAME | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 1999-08-11 | — | — | EP | disclosed |