Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 9/20 | 0.38 |
| ▸ | EPAS1 | Q99814 | 9/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1309456 | 0.72 | — | — | |
| SCHEMBL2818048 | 0.67 | — | — | |
| SCHEMBL9766726 | 0.66 | ALDH1A1 (0.53) | HIF1AEPAS1ALDH1A1MAPTCYP2A6 | |
| SCHEMBL29030402 | 0.64 | HIF1A (0.39) | HIF1AEPAS1ALDH1A1MAPTCYP2A6 | |
| SCHEMBL12967454 | 0.64 | KDM4E (0.43) | ALDH1A1MAPT | |
| SCHEMBL8594118 | 0.64 | HIF1A (0.40) | HIF1AEPAS1ALDH1A1MAPTCYP2A6 | |
| SCHEMBL8594116 | 0.64 | HIF1A (0.40) | HIF1AEPAS1ALDH1A1MAPTCYP2A6 | |
| SCHEMBL11173825 | 0.62 | — | — | |
| SCHEMBL7616986 | 0.62 | HIF1A (0.39) | HIF1AEPAS1ALDH1A1MAPTCYP2A6 | |
| SCHEMBL4968315 | 0.62 | HIF1A (0.39) | HIF1AEPAS1ALDH1A1MAPTCYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110357878-B | 1, 3-dihydro-2H-pyrrolo [3,2-b ] pyridin-2-one derivatives and medical use thereof | 武汉誉祥医药科技有限公司 | 2022-04-12 | — | — | CN | disclosed |