Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | HIF1A | Q16665 | 13/20 | 0.41 |
| ▸ | EPAS1 | Q99814 | 13/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
| ▸ | BLM | P54132 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1309456 | 0.84 | — | — | |
| SCHEMBL12687033 | 0.81 | ALDH1A1 (0.41) | ALDH1A1MAPTHIF1AEPAS1CYP2A6 | |
| SCHEMBL7047428 | 0.75 | ALDH1A1 (0.40) | ALDH1A1MAPTCYP2A6MEN1LMNA | |
| SCHEMBL2958085 | 0.75 | GAA (0.45) | ALDH1A1MAPTMEN1KMT2ARAB9A | |
| SCHEMBL3878366 | 0.74 | ALDH1A1 (0.40) | ALDH1A1MAPTHIF1AEPAS1LMNA | |
| SCHEMBL18946176 | 0.73 | ALDH1A1 (0.39) | ALDH1A1MAPTHIF1AEPAS1 | |
| SCHEMBL9227796 | 0.73 | MAPT (0.58) | ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL12989909 | 0.72 | — | — | |
| SCHEMBL2818048 | 0.72 | — | — | |
| SCHEMBL5917932 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5015478-A | Treatment of cancer with porphycene | CYTOPHARM, INC. (US) | 1991-05-14 | — | — | US | disclosed |
| US-4913907-A | LIPOSOMES | CYTOPHARM, INC. (US) | 1990-04-03 | — | — | US | disclosed |