Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | PARP1 | P09874 | 1/20 | 0.47 |
| ▸ | IKBKB | O14920 | 1/20 | 0.47 |
| ▸ | GRIN2B | Q13224 | 10/20 | 0.47 |
| ▸ | GRIN1 | Q05586 | 5/20 | 0.47 |
| ▸ | PIM1 | P11309 | 1/20 | 0.46 |
| ▸ | IDO1 | P14902 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22775716 | 1.00 | KDM4E (0.50) | KDM4ERAB9ASMN1; SMN2PARP1IKBKB | |
| SCHEMBL12907428 | 0.80 | HDAC1 (0.51) | IKBKBPIM1IDO1NOTUM | |
| SCHEMBL22775369 | 0.78 | GRIN2B (0.47) | KDM4ERAB9ASMN1; SMN2PARP1GRIN2B | |
| SCHEMBL20049822 | 0.76 | ALDH1A1 (0.51) | SMN1; SMN2PARP1GRIN2BGRIN1IDO1 | |
| SCHEMBL29525216 | 0.74 | GRIN1 (0.50) | GRIN2BGRIN1IDO1SCN2A | |
| SCHEMBL17759200 | 0.74 | GRIN1 (0.50) | GRIN2BGRIN1IDO1SCN2A | |
| SCHEMBL20171236 | 0.73 | ALDH1A1 (0.50) | SMN1; SMN2PARP1GRIN2BGRIN1ALDH1A1 | |
| SCHEMBL29636088 | 0.72 | PLK4 (0.65) | GRIN2BGRIN1PIM1 | |
| SCHEMBL28736423 | 0.72 | PLK4 (0.65) | GRIN2BGRIN1PIM1 | |
| SCHEMBL29636092 | 0.72 | PLK4 (0.65) | GRIN2BGRIN1PIM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3983075-A1 | SUBSTITUTED PYRAZOLO-PYRIDINE AMIDES AND THEIR USE AS GLUN2B RECEPTOR MODULATORS | Janssen Pharmaceutica NV (BE) | 2022-04-20 | — | — | EP | disclosed |