Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 10/20 | 0.63 |
| ▸ | DRD3 | P35462 | 9/20 | 0.63 |
| ▸ | DRD4 | P21917 | 7/20 | 0.63 |
| ▸ | CA1 | P00915 | 3/20 | 0.62 |
| ▸ | CA2 | P00918 | 3/20 | 0.62 |
| ▸ | ACHE | P22303 | 3/20 | 0.62 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.50 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.50 |
| ▸ | HTR1A | P08908 | 1/20 | 0.49 |
| ▸ | DRD1 | P21728 | 1/20 | 0.49 |
| ▸ | DRD5 | P21918 | 1/20 | 0.49 |
| ▸ | HTR7 | P34969 | 1/20 | 0.49 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2954959 | 0.85 | DRD2 (0.65) | DRD2DRD3DRD4CA1CA2 | |
| SCHEMBL14360233 | 0.84 | DRD2 (0.67) | DRD2DRD3DRD4CA1CA2 | |
| SCHEMBL2953314 | 0.82 | DRD2 (0.64) | DRD2DRD3DRD4CA1CA2 | |
| SCHEMBL2959295 | 0.81 | DRD2 (0.78) | DRD2DRD3DRD4CA1CA2 | |
| SCHEMBL2956868 | 0.81 | ADRA1D (0.49) | DRD2DRD3DRD4CA1CA2 | |
| SCHEMBL14360258 | 0.80 | DRD2 (0.79) | DRD2DRD3DRD4CA1CA2 | |
| SCHEMBL10357546 | 0.79 | CA1 (0.75) | DRD2DRD3DRD4CA1CA2 | |
| SCHEMBL1682786 | 0.78 | DRD2 (1.00) | DRD2DRD3DRD4CA1CA2 | |
| SCHEMBL1682783 | 0.78 | DRD2 (1.00) | DRD2DRD3DRD4CA1CA2 | |
| SCHEMBL17446169 | 0.78 | DRD2 (1.00) | DRD2DRD3DRD4CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1692096-B1 | HYDROXYLAMINE DERIVATIVES | NEWRON PHARM SPA (IT) | 2013-04-03 | — | — | EP | claimed |
| US-7763751-B2 | Hydroxylamine derivatives | NEWRON PHARMACEUTICALS S.P.A. (IT) | 2010-07-27 | — | — | US | claimed |
| US-20070049643-A1 | Hydroxylamine derivatives | VICURON PHARMACEUTICALS INC. | 2007-03-01 | — | — | US | claimed |
| EP-1541547-A1 | Hydroxylamine derivatives | Newron Pharmaceuticals S.p.A. (IT) | 2005-06-15 | — | — | EP | claimed |
| EP-1692096-B1 | HYDROXYLAMINE DERIVATIVES | NEWRON PHARM SPA (IT) | 2013-04-03 | — | — | EP | disclosed |
| US-20100197799-A1 | HYDROXYLAMINE DERIVATIVES | NEWRON PHARMACEUTICALS S.P.A. (IT) | 2010-08-05 | — | — | US | disclosed |
| US-7763751-B2 | Hydroxylamine derivatives | NEWRON PHARMACEUTICALS S.P.A. (IT) | 2010-07-27 | — | — | US | disclosed |
| US-20070049643-A1 | Hydroxylamine derivatives | VICURON PHARMACEUTICALS INC. | 2007-03-01 | — | — | US | disclosed |
| EP-1541547-A1 | Hydroxylamine derivatives | Newron Pharmaceuticals S.p.A. (IT) | 2005-06-15 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100197799-A1 | HYDROXYLAMINE DERIVATIVES | C9, C1S, HTT | DRD2 392/4885DRD3 245/4885DRD4 167/4885 |
| US-20070049643-A1 | Hydroxylamine derivatives | C9, C1S, HTT | DRD2 332/4885DRD3 161/4885DRD4 128/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.