Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 1/20 | 0.70 |
| ▸ | MAPT | P10636 | 4/20 | 0.59 |
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | CHRNB4 | P30926 | 4/20 | 0.53 |
| ▸ | CHRNA3 | P32297 | 4/20 | 0.53 |
| ▸ | CNR2 | P34972 | 1/20 | 0.51 |
| ▸ | CHRNB2 | P17787 | 4/20 | 0.50 |
| ▸ | CHRNA4 | P43681 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5198623 | 1.00 | AKR1C3 (0.70) | AKR1C3MAPTPOLBCHRNB4CHRNA3 | |
| SCHEMBL29998481 | 0.86 | CHRNB4 (0.61) | AKR1C3POLBCHRNB4CHRNA3CHRNB2 | |
| SCHEMBL27594106 | 0.82 | CHRNB4 (0.58) | AKR1C3MAPTPOLBCHRNB4CHRNA3 | |
| SCHEMBL27057850 | 0.82 | CHRNB4 (0.58) | AKR1C3POLBCHRNB4CHRNA3CHRNB2 | |
| SCHEMBL29932734 | 0.81 | CHRNB4 (0.56) | AKR1C3MAPTPOLBCHRNB4CHRNA3 | |
| SCHEMBL7186276 | 0.81 | CHRNB4 (0.56) | AKR1C3MAPTPOLBCHRNB4CHRNA3 | |
| SCHEMBL2001588 | 0.79 | CHRNB4 (0.54) | AKR1C3POLBCHRNB4CHRNA3CHRNB2 | |
| SCHEMBL1735480 | 0.79 | CNR2 (0.55) | AKR1C3MAPTPOLBCNR2MEN1 | |
| SCHEMBL1982257 | 0.78 | CHRNB4 (0.54) | AKR1C3POLBCHRNB4CHRNA3CHRNB2 | |
| SCHEMBL2923088 | 0.78 | CHRNB2 (0.64) | CHRNB4CHRNA3CHRNB2CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119730846-A | Kinase modulators and methods of use thereof | 神经元23公司 | 2025-03-28 | — | — | CN | disclosed |
| CN-110818641-B | Pyridazine-3-formamide compound, preparation method and application thereof in medicine and pharmacology | 北京诺诚健华医药科技有限公司 | 2022-10-14 | — | — | CN | disclosed |
| WO-2022032484-A1 | PYRIDAZINE-3-FORMAMIDE COMPOUND, AND PREPARATION METHOD THEREFOR AND MEDICAL USE THEREOF | 北京诺诚健华医药科技有限公司 | 2022-02-17 | — | — | WO | disclosed |