Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KARS1 | Q15046 | 4/20 | 0.58 |
| ▸ | RXRA | P19793 | 1/20 | 0.58 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.58 |
| ▸ | CDK2 | P24941 | 1/20 | 0.58 |
| ▸ | RXRB | P28702 | 1/20 | 0.58 |
| ▸ | RXRG | P48443 | 1/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.48 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.48 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.48 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29552613 | 0.78 | NR1I2 (0.41) | KARS1RXRACCNE1CDK2RXRB | |
| SCHEMBL28730781 | 0.76 | CYP3A4 (0.58) | KARS1RXRACCNE1CDK2RXRB | |
| SCHEMBL29553299 | 0.74 | CYP3A4 (0.43) | KARS1RXRACCNE1CDK2RXRB | |
| SCHEMBL29552419 | 0.74 | CYP3A4 (0.43) | KARS1RXRACCNE1CDK2RXRB | |
| Dehydroabietic Acid SCHEMBL14653170 | 0.74 | KARS1 (1.00) | KARS1RXRACCNE1CDK2RXRB | |
| Dehydroabietic Acid SCHEMBL15313390 | 0.74 | KARS1 (1.00) | KARS1RXRACCNE1CDK2RXRB | |
| Dehydroabietic Acid SCHEMBL222079 | 0.74 | KARS1 (1.00) | KARS1RXRACCNE1CDK2RXRB | |
| Dehydroabietic Acid SCHEMBL2603437 | 0.74 | KARS1 (1.00) | KARS1RXRACCNE1CDK2RXRB | |
| Dehydroabietic Acid SCHEMBL20061641 | 0.74 | KARS1 (1.00) | KARS1RXRACCNE1CDK2RXRB | |
| Dehydroabietic Acid SCHEMBL19798161 | 0.74 | KARS1 (1.00) | KARS1RXRACCNE1CDK2RXRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114480312-B | Abietane type tricyclic diterpenoid C-14 hydroxylase | 首都医科大学附属北京世纪坛医院 | 2024-04-16 | — | — | CN | disclosed |
| CN-114480312-A | C-14 hydroxylase of abietane type tricyclic diterpenoid compound | 首都医科大学附属北京世纪坛医院 | 2022-05-13 | — | — | CN | disclosed |
| CN-113648337-B | Application of tripterine in preparation of medicine for inhibiting replication of Marek's disease virus | 吉林大学 | 2022-04-29 | — | — | CN | disclosed |