Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KARS1 | Q15046 | 5/20 | 1.00 |
| ▸ | RXRA | P19793 | 1/20 | 1.00 |
| ▸ | CCNE1 | P24864 | 1/20 | 1.00 |
| ▸ | CDK2 | P24941 | 1/20 | 1.00 |
| ▸ | RXRB | P28702 | 1/20 | 1.00 |
| ▸ | RXRG | P48443 | 1/20 | 1.00 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.81 |
| ▸ | LMNA | P02545 | 1/20 | 0.81 |
| ▸ | POLB | P06746 | 1/20 | 0.67 |
| ▸ | APEX1 | P27695 | 1/20 | 0.67 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.67 |
| ▸ | MEN1 | O00255 | 3/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.64 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.64 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.64 |
| ▸ | TSHR | P16473 | 2/20 | 0.64 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.64 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.64 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.64 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dehydroabietic Acid SCHEMBL222078 | 1.00 | KARS1 (1.00) | KARS1RXRACCNE1CDK2RXRB | |
| Dehydroabietic Acid SCHEMBL15313390 | 1.00 | KARS1 (1.00) | KARS1RXRACCNE1CDK2RXRB | |
| Dehydroabietic Acid SCHEMBL14653170 | 1.00 | KARS1 (1.00) | KARS1RXRACCNE1CDK2RXRB | |
| Dehydroabietic Acid SCHEMBL222079 | 1.00 | KARS1 (1.00) | KARS1RXRACCNE1CDK2RXRB | |
| Dehydroabietic Acid SCHEMBL18019015 | 1.00 | KARS1 (1.00) | KARS1RXRACCNE1CDK2RXRB | |
| Dehydroabietic Acid SCHEMBL2603437 | 1.00 | KARS1 (1.00) | KARS1RXRACCNE1CDK2RXRB | |
| Dehydroabietic Acid SCHEMBL15744753 | 1.00 | KARS1 (1.00) | KARS1RXRACCNE1CDK2RXRB | |
| Dehydroabietic Acid SCHEMBL20061641 | 1.00 | KARS1 (1.00) | KARS1RXRACCNE1CDK2RXRB | |
| Dehydroabietic Acid SCHEMBL678991 | 1.00 | KARS1 (1.00) | KARS1RXRACCNE1CDK2RXRB | |
| Dehydroabietic Acid SCHEMBL9712221 | 1.00 | KARS1 (1.00) | KARS1RXRACCNE1CDK2RXRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180021303-A1 | BKCA CHANNEL ACTIVATOR FOR TREATING MUSCULAR DISORDER | CANBEX THERAPEUTICS LTD (GB) | 2018-01-25 | — | — | US | disclosed |
| US-20180021303-A1 | BKCA CHANNEL ACTIVATOR FOR TREATING MUSCULAR DISORDER | CANBEX THERAPEUTICS LTD (GB) | 2018-01-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180021303-A1 | BKCA CHANNEL ACTIVATOR FOR TREATING MUSCULAR DISORDER | KCNMA1, KCNMB1, KCNA1 | KARS1 440/4885RXRA 2511/4885CCNE1 4773/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.