SCHEMBL2955393

SCHEMBL2955393

C[SiH](C)[Zr]c1cccc2c1C=C1C2=Nc2ccccc21

nearest known ligand 0.35

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ABCG2 Q9UNQ0 1/20 0.35
IDO1 P14902 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28246158 0.75 ABCG2 (0.40) ABCG2IDO1
SCHEMBL1818065 0.74 ABCG2 (0.31) ABCG2
SCHEMBL4448185 0.73 ABCG2 (0.38) ABCG2IDO1
SCHEMBL1899426 0.72 ABCG2 (0.40) ABCG2IDO1
SCHEMBL4313632 0.72 ABCG2 (0.40) ABCG2IDO1
SCHEMBL1820364 0.72 ABCG2 (0.40) ABCG2IDO1
Hydrochloric Acid SCHEMBL4458472 0.71 ABCG2 (0.39) ABCG2IDO1
Hydrochloric Acid SCHEMBL4458471 0.71 ABCG2 (0.39) ABCG2IDO1
SCHEMBL9844740 0.70 ABCG2 (0.35) ABCG2IDO1
SCHEMBL3507971 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7776974-B2 Olefin polymerization process EQUISTAR CHEMICALS, LP (US) 2010-08-17 US disclosed
US-20090275711-A1 Olefin polymerization process EQUISTAR CHEMICALS, LP 2009-11-05 US disclosed