Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | APAF1 | O14727 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.31 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | HK1 | P19367 | 1/20 | 0.31 |
| ▸ | GALK1 | P51570 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1820364 | 0.78 | ABCG2 (0.40) | ABCG2IDO1KDM4EMEN1APAF1 | |
| SCHEMBL4313632 | 0.78 | ABCG2 (0.40) | ABCG2IDO1KDM4EMEN1APAF1 | |
| SCHEMBL28246158 | 0.78 | ABCG2 (0.40) | ABCG2IDO1KDM4EMEN1APAF1 | |
| SCHEMBL1899426 | 0.78 | ABCG2 (0.40) | ABCG2IDO1KDM4EMEN1APAF1 | |
| Hydrochloric Acid SCHEMBL4458471 | 0.77 | ABCG2 (0.39) | ABCG2IDO1KDM4EMEN1APAF1 | |
| SCHEMBL4448185 | 0.75 | ABCG2 (0.38) | ABCG2IDO1KDM4EMEN1APAF1 | |
| SCHEMBL9844740 | 0.72 | ABCG2 (0.35) | ABCG2IDO1 | |
| Hydrochloric Acid SCHEMBL4458466 | 0.71 | ABCG2 (0.66) | ABCG2IDO1 | |
| SCHEMBL2955393 | 0.71 | ABCG2 (0.35) | ABCG2IDO1 | |
| SCHEMBL261676 | 0.71 | ABCG2 (0.62) | ABCG2IDO1KDM4EMEN1APAF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009032048-A1 | OLEFIN POLYMERIZATION PROCESS | EQUISTAR CHEMICALS, LP (US) | 2009-03-12 | — | — | WO | disclosed |
| EP-1551883-A1 | SUPPORTED CATALYSTS FOR GAS PHASE OLEFIN POLYMERIZATION | Equistar Chemicals, LP (US) | 2005-07-13 | — | — | EP | disclosed |
| WO-2004035634-A1 | SUPPORTED CATALYSTS FOR GAS PHASE OLEFIN POLYMERIZATION | EQUISTAR CHEMICALS, LP (US) | 2004-04-29 | — | — | WO | disclosed |