Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | APAF1 | O14727 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.30 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | HK1 | P19367 | 1/20 | 0.30 |
| ▸ | GALK1 | P51570 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4448189 | 0.81 | — | — | |
| SCHEMBL28246158 | 0.80 | ABCG2 (0.40) | ABCG2IDO1KDM4EMEN1APAF1 | |
| SCHEMBL1820364 | 0.77 | ABCG2 (0.40) | ABCG2IDO1KDM4EMEN1APAF1 | |
| SCHEMBL4313632 | 0.77 | ABCG2 (0.40) | ABCG2IDO1KDM4EMEN1APAF1 | |
| SCHEMBL1899426 | 0.77 | ABCG2 (0.40) | ABCG2IDO1KDM4EMEN1APAF1 | |
| Hydrochloric Acid SCHEMBL4458471 | 0.75 | ABCG2 (0.39) | ABCG2IDO1KDM4EMEN1APAF1 | |
| Hydrochloric Acid SCHEMBL4458472 | 0.75 | ABCG2 (0.39) | ABCG2IDO1KDM4EMEN1APAF1 | |
| SCHEMBL9844740 | 0.74 | ABCG2 (0.35) | ABCG2IDO1 | |
| SCHEMBL2955393 | 0.73 | ABCG2 (0.35) | ABCG2IDO1 | |
| SCHEMBL9738584 | 0.70 | ABCG2 (0.34) | ABCG2IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1567561-B1 | BIMETALLIC INDENOINDOLYL CATALYSTS | EQUISTAR CHEM LP (US) | 2009-05-27 | — | — | EP | disclosed |
| EP-1567561-A1 | BIMETALLIC INDENOINDOLYL CATALYSTS | Equistar Chemicals, LP (US) | 2005-08-31 | — | — | EP | disclosed |
| US-6841500-B2 | Bimetallic indenoindolyl catalysts | EQUISTAR CHEMICALS, LP (US) | 2005-01-11 | — | — | US | disclosed |
| WO-2004050718-A1 | BIMETALLIC INDENOINDOLYL CATALYSTS | EQUISTAR CHEMICALS, LP (US) | 2004-06-17 | — | — | WO | disclosed |
| US-20040106514-A1 | Bimetallic indenoindolyl catalysts | EQUISTAR CHEMICALS, LP | 2004-06-03 | — | — | US | disclosed |