Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 4/20 | 0.47 |
| ▸ | FABP4 | P15090 | 3/20 | 0.45 |
| ▸ | FABP3 | P05413 | 1/20 | 0.45 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | EDNRA | P25101 | 5/20 | 0.40 |
| ▸ | EDNRB | P24530 | 5/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | DHODH | Q02127 | 1/20 | 0.40 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MC4R | P32245 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2955440 | 0.98 | ALOX5 (0.47) | ALOX5FABP4FABP3FABP5KMT2A | |
| SCHEMBL2955437 | 0.89 | ALOX5 (0.47) | ALOX5FABP4FABP3FABP5KMT2A | |
| SCHEMBL2955722 | 0.88 | ALOX5 (0.47) | ALOX5FABP4FABP3FABP5KMT2A | |
| SCHEMBL2960583 | 0.88 | ALOX5 (0.47) | ALOX5FABP4FABP3FABP5KMT2A | |
| SCHEMBL2960587 | 0.86 | ALOX5 (0.47) | ALOX5FABP4FABP3FABP5KMT2A | |
| SCHEMBL2955144 | 0.83 | ALOX5 (0.51) | ALOX5FABP4FABP3FABP5KMT2A | |
| SCHEMBL2955149 | 0.81 | ALOX5 (0.51) | ALOX5FABP4FABP3FABP5KMT2A | |
| SCHEMBL2960584 | 0.77 | ALOX5 (0.47) | ALOX5FABP4FABP3FABP5EDNRA | |
| SCHEMBL2955725 | 0.77 | ALOX5 (0.47) | ALOX5KMT2AEDNRAEDNRBTP53 | |
| SCHEMBL2955145 | 0.72 | ALOX5 (0.50) | ALOX5FABP4FABP3FABP5EDNRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080167353-A1 | Novel Antiviral Helioxanthin Analogs | YALE UNIVERSITY (US) | 2008-07-10 | — | — | US | claimed |
| WO-2005107742-A1 | NOVEL ANTIVIRAL HELIOXANTHIN ANALOGS | YALE UNIVERSITY (US) | 2005-11-17 | — | — | WO | claimed |
| US-7754718-B2 | Antiviral helioxanthin analogs | YALE UNIVERSITY (US) | 2010-07-13 | — | — | US | disclosed |
| US-20080167353-A1 | Novel Antiviral Helioxanthin Analogs | YALE UNIVERSITY (US) | 2008-07-10 | — | — | US | disclosed |
| WO-2005107742-A1 | NOVEL ANTIVIRAL HELIOXANTHIN ANALOGS | YALE UNIVERSITY (US) | 2005-11-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080167353-A1 | Novel Antiviral Helioxanthin Analogs | HAVCR2, ZC3HAV1, DHX35 | ALOX5 2383/4885FABP4 4584/4885FABP3 4031/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.