Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 5/20 | 0.51 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | DHODH | Q02127 | 1/20 | 0.42 |
| ▸ | FABP4 | P15090 | 2/20 | 0.41 |
| ▸ | FABP3 | P05413 | 1/20 | 0.41 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MC4R | P32245 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2955144 | 0.98 | ALOX5 (0.51) | ALOX5CTNNB1TP53DHODHFABP4 | |
| SCHEMBL2955145 | 0.88 | ALOX5 (0.50) | ALOX5CTNNB1TP53DHODHFABP4 | |
| SCHEMBL6913771 | 0.86 | ALOX5 (0.48) | ALOX5KDM4EALDH1A1PKMHPGD | |
| SCHEMBL2957205 | 0.84 | CTNNB1 (0.46) | ALOX5CTNNB1TP53DHODHFABP4 | |
| SCHEMBL6913485 | 0.83 | ALOX5 (0.72) | ALOX5KDM4EALDH1A1EDNRBEDNRA | |
| SCHEMBL6914615 | 0.83 | TARBP2 (0.46) | ALOX5TP53KDM4EALDH1A1PKM | |
| SCHEMBL2960587 | 0.83 | ALOX5 (0.47) | ALOX5CTNNB1TP53DHODHFABP4 | |
| SCHEMBL2955440 | 0.83 | ALOX5 (0.47) | ALOX5CTNNB1TP53DHODHFABP4 | |
| Ammonia Solution, Strong SCHEMBL6532360 | 0.83 | CTNNB1 (0.46) | ALOX5CTNNB1TP53DHODHFABP4 | |
| SCHEMBL7659655 | 0.83 | ALDH1A1 (0.46) | ALOX5CTNNB1TP53DHODHFABP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7754718-B2 | Antiviral helioxanthin analogs | YALE UNIVERSITY (US) | 2010-07-13 | — | — | US | disclosed |
| US-20080167353-A1 | Novel Antiviral Helioxanthin Analogs | YALE UNIVERSITY (US) | 2008-07-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080167353-A1 | Novel Antiviral Helioxanthin Analogs | HAVCR2, ZC3HAV1, DHX35 | ALOX5 2383/4885CTNNB1 3055/4885TP53 1292/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.