Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.52 |
| ▸ | TP53 | P04637 | 4/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.52 |
| ▸ | ATM | Q13315 | 2/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | GBA1 | P04062 | 2/20 | 0.50 |
| ▸ | CA12 | O43570 | 2/20 | 0.50 |
| ▸ | CA9 | Q16790 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29095258 | 0.90 | MAPT (0.56) | MAPTTP53LMNACYP1A2CYP3A4 | |
| SCHEMBL29095242 | 0.87 | MAPT (0.43) | MAPTTP53LMNACYP1A2CYP3A4 | |
| SCHEMBL29554998 | 0.85 | TP53 (0.55) | MAPTTP53LMNACYP1A2CYP3A4 | |
| SCHEMBL17793671 | 0.83 | GBA1 (0.51) | TP53LMNASMN1; SMN2GBA1ALDH1A1 | |
| SCHEMBL29555080 | 0.76 | TP53 (0.52) | MAPTTP53LMNACYP1A2CYP3A4 | |
| SCHEMBL28398278 | 0.76 | MAPT (0.52) | MAPTTP53GAAMEN1CYP2C19 | |
| SCHEMBL4986451 | 0.76 | GBA1 (0.79) | MAPTTP53LMNACYP1A2CYP3A4 | |
| SCHEMBL12879312 | 0.76 | GBA1 (0.79) | MAPTTP53LMNACYP1A2CYP3A4 | |
| SCHEMBL17793668 | 0.76 | TP53 (0.58) | MAPTTP53LMNACYP1A2CYP3A4 | |
| SCHEMBL27807197 | 0.76 | GBA1 (0.79) | MAPTTP53LMNACYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114315660-A | Method for preparing 2-aryl phenethylamine derivative | 江苏海洋大学 | 2022-04-12 | — | — | CN | disclosed |