Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.56 |
| ▸ | MEN1 | O00255 | 4/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | TP53 | P04637 | 3/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.56 |
| ▸ | GAA | P10253 | 2/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | ATM | Q13315 | 1/20 | 0.56 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | GBA1 | P04062 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29555017 | 0.90 | MAPT (0.52) | MAPTMEN1KMT2ALMNATP53 | |
| SCHEMBL17793671 | 0.81 | GBA1 (0.51) | LMNATP53SMN1; SMN2CA1CA2 | |
| SCHEMBL29095242 | 0.80 | MAPT (0.43) | MAPTMEN1KMT2ALMNATP53 | |
| SCHEMBL17793670 | 0.78 | CA1 (0.64) | MAPTMEN1KMT2ALMNATP53 | |
| SCHEMBL28910541 | 0.78 | MAPT (0.58) | MAPTMEN1KMT2ALMNATP53 | |
| SCHEMBL29554998 | 0.75 | TP53 (0.55) | MAPTMEN1KMT2ALMNATP53 | |
| SCHEMBL14493818 | 0.73 | SLC6A2 (0.46) | MAPTMEN1KMT2ALMNATP53 | |
| SCHEMBL29019360 | 0.73 | HDAC3 (0.68) | MEN1KMT2ALMNATP53SMN1; SMN2 | |
| SCHEMBL7417547 | 0.72 | MMP7 (0.69) | MAPTCA1CA2ALDH1A1 | |
| SCHEMBL7417364 | 0.72 | MMP7 (0.69) | MAPTCA1CA2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114315660-B | Method for preparing 2-arylphenethylamine derivative | 江苏海洋大学 | 2023-09-22 | — | — | CN | disclosed |
| CN-114315660-A | Method for preparing 2-aryl phenethylamine derivative | 江苏海洋大学 | 2022-04-12 | — | — | CN | disclosed |