Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 14/20 | 1.00 |
| ▸ | BCR | P11274 | 12/20 | 1.00 |
| ▸ | PRKCA | P17252 | 3/20 | 0.73 |
| ▸ | PDGFRA | P16234 | 7/20 | 0.68 |
| ▸ | PDGFRB | P09619 | 6/20 | 0.68 |
| ▸ | EGFR | P00533 | 5/20 | 0.67 |
| ▸ | SRC | P12931 | 1/20 | 0.67 |
| ▸ | PRKACA | P17612 | 1/20 | 0.67 |
| ▸ | PRKACG | P22612 | 1/20 | 0.67 |
| ▸ | PRKACB | P22694 | 1/20 | 0.67 |
| ▸ | JAK3 | P52333 | 1/20 | 0.63 |
| ▸ | BTK | Q06187 | 1/20 | 0.63 |
| ▸ | ITK | Q08881 | 1/20 | 0.63 |
| ▸ | KIT | P10721 | 2/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2392 | 1.00 | ABL1 (1.00) | ABL1BCRPRKCAPDGFRAPDGFRB | |
| SCHEMBL29366999 | 1.00 | ABL1 (1.00) | ABL1BCRPRKCAPDGFRAPDGFRB | |
| Ammonia Solution, Strong SCHEMBL4749564 | 0.99 | ABL1 (0.98) | ABL1BCRPRKCAPDGFRAPDGFRB | |
| Hydrochloric Acid SCHEMBL2419016 | 0.99 | ABL1 (0.98) | ABL1BCRPRKCAPDGFRAPDGFRB | |
| SCHEMBL14938216 | 0.92 | ABL1 (0.85) | ABL1BCRPRKCAPDGFRAPDGFRB | |
| SCHEMBL3860532 | 0.91 | ABL1 (0.83) | ABL1BCRPRKCAPDGFRAPDGFRB | |
| SCHEMBL2575958 | 0.88 | ABL1 (0.78) | ABL1BCRPRKCAPDGFRAPDGFRB | |
| SCHEMBL12320924 | 0.88 | ABL1 (0.78) | ABL1BCRPRKCAPDGFRAPDGFRB | |
| SCHEMBL7601457 | 0.88 | ABL1 (0.78) | ABL1BCRPRKCAPDGFRAPDGFRB | |
| SCHEMBL14041906 | 0.87 | ABL1 (0.78) | ABL1BCRPRKCAPDGFRAPDGFRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112125882-B | Method for synthesizing imatinib free base | 山东汇海医药化工有限公司 | 2023-04-11 | — | — | CN | claimed |
| CN-114685428-A | Preparation method of imatinib mesylate | 重庆圣华曦药业股份有限公司 | 2022-07-01 | — | — | CN | claimed |
| CN-114315595-B | Preparation method of carbon-supported iron-based catalyst and application of intermediate synthesis of anticancer inhibitor of carbon-supported iron-based catalyst | 奥锐特药业股份有限公司 | 2023-12-05 | — | — | CN | disclosed |
| CN-113004252-B | Aryl imidazole derivative and application thereof | 江苏先声药业有限公司 | 2023-06-09 | — | — | CN | disclosed |
| WO-2023098592-A1 | PREPARATION METHOD FOR CARBON-LOADED IRON-BASED CATALYST AND USE THEREOF IN SYNTHESIS OF INTERMEDIATES OF ANTI-CANCER INHIBITORS | 奥锐特药业股份有限公司 | 2023-06-08 | — | — | WO | disclosed |
| CN-112125882-B | Method for synthesizing imatinib free base | 山东汇海医药化工有限公司 | 2023-04-11 | — | — | CN | disclosed |
| CN-112125882-B | Method for synthesizing imatinib free base | 山东汇海医药化工有限公司 | 2023-04-11 | — | — | CN | disclosed |
| WO-2023283369-A1 | MODULATORS OF PROTEIN KINASES | VIBLIOME THERAPEUTICS, LLC (US) | 2023-01-12 | — | — | WO | disclosed |
| EP-4045494-A1 | SYNTHESIS OF 6-METHYL-N1-(4-(PYRIDIN-3-YL)PYRIMIDIN-2-YL)BENZENE-1,3-DIAMINE | Esco Aster Pte. Ltd. (SG) | 2022-08-24 | — | — | EP | disclosed |
| CN-114685428-A | Preparation method of imatinib mesylate | 重庆圣华曦药业股份有限公司 | 2022-07-01 | — | — | CN | disclosed |
| CN-114685428-A | Preparation method of imatinib mesylate | 重庆圣华曦药业股份有限公司 | 2022-07-01 | — | — | CN | disclosed |
| CN-114585615-A | Synthesis of 6-methyl-N1- (4- (pyridin-3-yl) pyrimidin-2-yl) benzene-1, 3-diamine | 新加坡艺思高艾斯特生物科技有限公司 | 2022-06-03 | — | — | CN | disclosed |
| CN-114585615-A | Synthesis of 6-methyl-N1- (4- (pyridin-3-yl) pyrimidin-2-yl) benzene-1, 3-diamine | 新加坡艺思高艾斯特生物科技有限公司 | 2022-06-03 | — | — | CN | disclosed |
| CN-114315595-A | Preparation method of carbon-supported iron-based catalyst and synthesis application of anti-cancer inhibitor intermediate thereof | 湖南大学 | 2022-04-12 | — | — | CN | disclosed |