Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 14/20 | 0.98 |
| ▸ | BCR | P11274 | 12/20 | 0.98 |
| ▸ | PRKCA | P17252 | 3/20 | 0.72 |
| ▸ | PDGFRA | P16234 | 7/20 | 0.67 |
| ▸ | PDGFRB | P09619 | 6/20 | 0.67 |
| ▸ | EGFR | P00533 | 5/20 | 0.65 |
| ▸ | SRC | P12931 | 1/20 | 0.65 |
| ▸ | PRKACA | P17612 | 1/20 | 0.65 |
| ▸ | PRKACG | P22612 | 1/20 | 0.65 |
| ▸ | PRKACB | P22694 | 1/20 | 0.65 |
| ▸ | JAK3 | P52333 | 1/20 | 0.62 |
| ▸ | BTK | Q06187 | 1/20 | 0.62 |
| ▸ | ITK | Q08881 | 1/20 | 0.62 |
| ▸ | KIT | P10721 | 2/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29366999 | 0.99 | ABL1 (1.00) | ABL1BCRPRKCAPDGFRAPDGFRB | |
| SCHEMBL29555505 | 0.99 | ABL1 (1.00) | ABL1BCRPRKCAPDGFRAPDGFRB | |
| SCHEMBL2392 | 0.99 | ABL1 (1.00) | ABL1BCRPRKCAPDGFRAPDGFRB | |
| Hydrochloric Acid SCHEMBL2419016 | 0.98 | ABL1 (0.98) | ABL1BCRPRKCAPDGFRAPDGFRB | |
| SCHEMBL14938216 | 0.91 | ABL1 (0.85) | ABL1BCRPRKCAPDGFRAPDGFRB | |
| SCHEMBL3860532 | 0.89 | ABL1 (0.83) | ABL1BCRPRKCAPDGFRAPDGFRB | |
| SCHEMBL2575958 | 0.87 | ABL1 (0.78) | ABL1BCRPRKCAPDGFRAPDGFRB | |
| SCHEMBL12320924 | 0.87 | ABL1 (0.78) | ABL1BCRPRKCAPDGFRAPDGFRB | |
| SCHEMBL7601457 | 0.87 | ABL1 (0.78) | ABL1BCRPRKCAPDGFRAPDGFRB | |
| SCHEMBL14041906 | 0.86 | ABL1 (0.78) | ABL1BCRPRKCAPDGFRAPDGFRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008117298-A1 | A NOVEL METHOD OF PREPARATION OF IMATINIB | NATCO PHARMA LIMITED (IN) | 2008-10-02 | — | — | WO | claimed |
| WO-2008117298-A1 | A NOVEL METHOD OF PREPARATION OF IMATINIB | NATCO PHARMA LIMITED (IN) | 2008-10-02 | — | — | WO | disclosed |
| WO-2008117298-A1 | A NOVEL METHOD OF PREPARATION OF IMATINIB | NATCO PHARMA LIMITED (IN) | 2008-10-02 | — | — | WO | disclosed |