Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 1/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.49 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.46 |
| ▸ | SMARCA2 | P51531 | 2/20 | 0.45 |
| ▸ | SMARCA4 | P51532 | 2/20 | 0.45 |
| ▸ | AR | P10275 | 4/20 | 0.43 |
| ▸ | RAF1 | P04049 | 1/20 | 0.42 |
| ▸ | BRAF | P15056 | 3/20 | 0.42 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.41 |
| ▸ | IDH1 | O75874 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29555582 | 0.88 | SMARCA2 (0.60) | HDAC3HDAC1HDAC2HDAC6EPHX2 | |
| SCHEMBL29555831 | 0.87 | HDAC3 (0.47) | HDAC3HDAC1HDAC2HDAC6EPHX2 | |
| SCHEMBL29555845 | 0.84 | ALDH1A1 (0.49) | SMARCA2SMARCA4ARKDRNPC1 | |
| SCHEMBL29556113 | 0.84 | P2RY1 (0.55) | SMARCA2SMARCA4ARP2RY1NPC1 | |
| SCHEMBL29555904 | 0.81 | EPHX2 (0.52) | HDAC3HDAC1HDAC2HDAC6EPHX2 | |
| SCHEMBL29556929 | 0.81 | MAPT (0.50) | HDAC3HDAC1HDAC2HDAC6EPHX2 | |
| SCHEMBL29556206 | 0.80 | MEN1 (0.50) | SMARCA2SMARCA4ARP2RY1NPC1 | |
| SCHEMBL29556142 | 0.80 | MEN1 (0.62) | EPHX2NPC1RAB9AP2RX1MEN1 | |
| SCHEMBL29555858 | 0.80 | MEN1 (0.62) | EPHX2NPC1RAB9AP2RX1MEN1 | |
| SCHEMBL29556394 | 0.79 | EPHX2 (0.49) | HDAC3HDAC1HDAC2HDAC6EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022078533-A1 | SUBSTITUTED 1,3-DIPHENYLUREA DERIVATIVES AND 1-PHENYL-3-PYRIDYLUREA DERIVATIVES FOR PLANT BIOTECHNOLOGY, PREPARATIONS CONTAINING THESE COMPOUNDS AND USE THEREOF | USTAV EXPERIMENTALNI BOTANIKY AV CR, V.V.I. (CZ) | 2022-04-21 | — | — | WO | disclosed |