Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | AR | P10275 | 1/20 | 0.48 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.47 |
| ▸ | KDR | P35968 | 1/20 | 0.47 |
| ▸ | CNR1 | P21554 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 7/20 | 0.46 |
| ▸ | NPC1 | O15118 | 6/20 | 0.46 |
| ▸ | MAPT | P10636 | 5/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | HTT | P42858 | 3/20 | 0.45 |
| ▸ | TP53 | P04637 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | SMARCA2 | P51531 | 2/20 | 0.45 |
| ▸ | SMARCA4 | P51532 | 2/20 | 0.45 |
| ▸ | IDH1 | O75874 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | VSIG8 | P0DPA2 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29556246 | 0.87 | SMARCA2 (0.60) | ALDH1A1PDGFRAKDRCNR1RAB9A | |
| SCHEMBL29556113 | 0.87 | P2RY1 (0.55) | ALDH1A1ARCNR1RAB9ANPC1 | |
| SCHEMBL29556191 | 0.85 | MAPT (0.51) | ALDH1A1PDGFRAKDRCNR1RAB9A | |
| SCHEMBL29555865 | 0.84 | HDAC3 (0.49) | ARKDRRAB9ANPC1MEN1 | |
| SCHEMBL29556614 | 0.83 | ALDH1A1 (0.71) | ALDH1A1PDGFRARAB9ANPC1MAPT | |
| SCHEMBL29555889 | 0.81 | MAPT (0.56) | CNR1RAB9ANPC1MAPTSMN1; SMN2 | |
| SCHEMBL29556206 | 0.81 | MEN1 (0.50) | ALDH1A1ARCNR1RAB9ANPC1 | |
| SCHEMBL29555952 | 0.80 | CNR1 (0.60) | ALDH1A1PDGFRAKDRCNR1RAB9A | |
| SCHEMBL29556385 | 0.80 | RAB9A (0.46) | ALDH1A1RAB9ANPC1MAPTSMN1; SMN2 | |
| SCHEMBL29555881 | 0.80 | RAB9A (0.46) | ALDH1A1RAB9ANPC1MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022078533-A1 | SUBSTITUTED 1,3-DIPHENYLUREA DERIVATIVES AND 1-PHENYL-3-PYRIDYLUREA DERIVATIVES FOR PLANT BIOTECHNOLOGY, PREPARATIONS CONTAINING THESE COMPOUNDS AND USE THEREOF | USTAV EXPERIMENTALNI BOTANIKY AV CR, V.V.I. (CZ) | 2022-04-21 | — | — | WO | disclosed |