Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT1 | Q99873 | 3/20 | 0.76 |
| ▸ | APP | P05067 | 6/20 | 0.66 |
| ▸ | NPC1 | O15118 | 5/20 | 0.66 |
| ▸ | RAB9A | P51151 | 5/20 | 0.66 |
| ▸ | APAF1 | O14727 | 2/20 | 0.66 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.66 |
| ▸ | ALPL | P05186 | 1/20 | 0.66 |
| ▸ | ITGAM | P11215 | 1/20 | 0.66 |
| ▸ | GFER | P55789 | 1/20 | 0.66 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.66 |
| ▸ | MEN1 | O00255 | 6/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.64 |
| ▸ | HTT | P42858 | 5/20 | 0.64 |
| ▸ | BLM | P54132 | 4/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.61 |
| ▸ | POLB | P06746 | 3/20 | 0.61 |
| ▸ | MAPT | P10636 | 3/20 | 0.61 |
| ▸ | RECQL | P46063 | 3/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.61 |
| ▸ | THRB | P10828 | 2/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodide SCHEMBL26664753 | 1.00 | PRMT1 (0.76) | PRMT1APPNPC1RAB9AAPAF1 | |
| Iodide SCHEMBL26664754 | 1.00 | PRMT1 (0.76) | PRMT1APPNPC1RAB9AAPAF1 | |
| SCHEMBL26794997 | 0.99 | PRMT1 (0.74) | PRMT1APPNPC1RAB9AAPAF1 | |
| SCHEMBL27391249 | 0.86 | PRMT1 (0.75) | PRMT1APPNPC1RAB9AAPAF1 | |
| Hydrochloric Acid SCHEMBL26664761 | 0.84 | PRMT1 (0.73) | PRMT1APPNPC1RAB9AAPAF1 | |
| Hydrochloric Acid SCHEMBL26664765 | 0.84 | PRMT1 (0.73) | PRMT1APPNPC1RAB9AAPAF1 | |
| Hydrochloric Acid SCHEMBL29556620 | 0.84 | PRMT1 (0.73) | PRMT1APPNPC1RAB9AAPAF1 | |
| Iodide SCHEMBL10821222 | 0.84 | PRMT1 (0.70) | PRMT1APPNPC1RAB9AAPAF1 | |
| SCHEMBL18070601 | 0.82 | PRMT1 (0.70) | PRMT1APPNPC1RAB9AAPAF1 | |
| Hydrochloric Acid SCHEMBL11536389 | 0.82 | PRMT1 (0.67) | PRMT1APPNPC1RAB9AAPAF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4228631-A1 | FLAVI-BLOCK: A PAN-FLAVIVIRUS INHIBITOR | Baden-Württemberg Stiftung gGmbH (DE) | 2023-08-23 | — | — | EP | disclosed |
| WO-2022078602-A1 | FLAVI-BLOCK: A PAN-FLAVIVIRUS INHIBITOR | BADEN-WÜRTTEMBERG STIFTUNG GGMBH (DE) | 2022-04-21 | — | — | WO | disclosed |