Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT1 | Q99873 | 3/20 | 0.76 |
| ▸ | APP | P05067 | 6/20 | 0.66 |
| ▸ | NPC1 | O15118 | 5/20 | 0.66 |
| ▸ | RAB9A | P51151 | 5/20 | 0.66 |
| ▸ | APAF1 | O14727 | 2/20 | 0.66 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.66 |
| ▸ | ALPL | P05186 | 1/20 | 0.66 |
| ▸ | ITGAM | P11215 | 1/20 | 0.66 |
| ▸ | GFER | P55789 | 1/20 | 0.66 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.66 |
| ▸ | MEN1 | O00255 | 6/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.64 |
| ▸ | HTT | P42858 | 5/20 | 0.64 |
| ▸ | BLM | P54132 | 4/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.61 |
| ▸ | POLB | P06746 | 3/20 | 0.61 |
| ▸ | MAPT | P10636 | 3/20 | 0.61 |
| ▸ | RECQL | P46063 | 3/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.61 |
| ▸ | THRB | P10828 | 2/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodide SCHEMBL26664754 | 1.00 | PRMT1 (0.76) | PRMT1APPNPC1RAB9AAPAF1 | |
| Iodide SCHEMBL29556031 | 1.00 | PRMT1 (0.76) | PRMT1APPNPC1RAB9AAPAF1 | |
| SCHEMBL26794997 | 0.99 | PRMT1 (0.74) | PRMT1APPNPC1RAB9AAPAF1 | |
| SCHEMBL27391249 | 0.86 | PRMT1 (0.75) | PRMT1APPNPC1RAB9AAPAF1 | |
| Hydrochloric Acid SCHEMBL26664761 | 0.84 | PRMT1 (0.73) | PRMT1APPNPC1RAB9AAPAF1 | |
| Hydrochloric Acid SCHEMBL26664765 | 0.84 | PRMT1 (0.73) | PRMT1APPNPC1RAB9AAPAF1 | |
| Hydrochloric Acid SCHEMBL29556620 | 0.84 | PRMT1 (0.73) | PRMT1APPNPC1RAB9AAPAF1 | |
| Iodide SCHEMBL10821222 | 0.84 | PRMT1 (0.70) | PRMT1APPNPC1RAB9AAPAF1 | |
| SCHEMBL18070601 | 0.82 | PRMT1 (0.70) | PRMT1APPNPC1RAB9AAPAF1 | |
| Hydrochloric Acid SCHEMBL11536389 | 0.82 | PRMT1 (0.67) | PRMT1APPNPC1RAB9AAPAF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12527773-B2 | Flavi-block: a pan-flavivirus inhibitor | BADEN-WÜRTTEMBERG STIFTUNG GMBH (US) | 2026-01-20 | — | — | US | disclosed |
| EP-4228631-B1 | FLAVI-BLOCK: A PAN-FLAVIVIRUS INHIBITOR | BADEN WUERTTEMBERG STIFTUNG GMBH (DE) | 2024-08-21 | — | — | EP | disclosed |
| US-20230372310-A1 | Flavi-Block: A Pan-Flavivirus Inhibitor | BADEN-WÜRTTEMBERG STIFTUNG GMBH (DE) | 2023-11-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12527773-B2 | Flavi-block: a pan-flavivirus inhibitor | EIF2B5, EIF2B1, EIF2B2 | PRMT1 827/4885APP 2153/4885NPC1 1064/4885 |
| US-20230372310-A1 | Flavi-Block: A Pan-Flavivirus Inhibitor | MAVS, EIF2AK2, BLVRB | PRMT1 3292/4885APP 2351/4885NPC1 1460/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.