Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 3/20 | 1.00 |
| ▸ | PKM | P14618 | 10/20 | 0.61 |
| ▸ | NLRP3 | Q96P20 | 2/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | TP53 | P04637 | 3/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | STAT6 | P42226 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | CASP1 | P29466 | 1/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.45 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.45 |
| ▸ | RELA | Q04206 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | THPO | P40225 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Micheliolide SCHEMBL18334099 | 0.76 | PKM (1.00) | CYP19A1PKMNLRP3ALDH1A1LMNA | |
| Micheliolide SCHEMBL22375104 | 0.76 | PKM (1.00) | CYP19A1PKMNLRP3ALDH1A1LMNA | |
| Micheliolide SCHEMBL22354429 | 0.76 | PKM (1.00) | CYP19A1PKMNLRP3ALDH1A1LMNA | |
| Moroccolide A SCHEMBL31238194 | 0.75 | CYP19A1 (0.60) | CYP19A1PKMNLRP3ALDH1A1LMNA | |
| SCHEMBL24982735 | 0.73 | PKM (0.69) | CYP19A1PKMNLRP3ALDH1A1LMNA | |
| SCHEMBL31055344 | 0.71 | CYP19A1 (0.55) | CYP19A1PKMNLRP3MAPTPTGS2 | |
| SCHEMBL29756635 | 0.69 | CYP19A1 (0.53) | CYP19A1PKMNLRP3ALDH1A1LMNA | |
| SCHEMBL22388762 | 0.69 | PKM (0.63) | CYP19A1PKMNLRP3ALDH1A1LMNA | |
| SCHEMBL22354262 | 0.69 | PKM (0.56) | CYP19A1PKMNLRP3ALDH1A1LMNA | |
| SCHEMBL14900972 | 0.69 | PKM (0.64) | CYP19A1PKMNLRP3ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4403559-B1 | GUAIANE SESQUITERPENE POLYMER AND PREPARATION METHOD THEREFOR AND USE THEREOF | KUNMING INST BOTANY CAS (CN) | 2026-01-28 | — | — | EP | claimed |
| US-20240409552-A1 | GUAIANOLIDE OLIGOMERS, PREPARATION METHOD AND APPLICATION | KUNMING INSTITUTE OF BOTANY, CHINESE ACADEMY OF SCIENCES (CN) | 2024-12-12 | — | — | US | claimed |
| EP-4403559-A1 | GUAIANE SESQUITERPENE POLYMER AND PREPARATION METHOD THEREFOR AND USE THEREOF | Kunming Institute of Botany, Chinese Academy of Sciences (CN) | 2024-07-24 | — | — | EP | claimed |
| CN-113788840-B | Guaiane sesquiterpene polymer and medicine thereof, and preparation method and application thereof | 中国科学院昆明植物研究所 | 2023-08-11 | — | — | CN | claimed |
| WO-2023040703-A1 | GUAIANE SESQUITERPENE POLYMER AND PREPARATION METHOD THEREFOR AND USE THEREOF | 中国科学院昆明植物研究所 | 2023-03-23 | — | — | WO | claimed |
| CN-114539195-A | Ludartin derivative, pharmaceutical composition thereof, preparation method and application thereof | 中国科学院昆明植物研究所 | 2022-05-27 | — | — | CN | claimed |
| EP-4403559-B1 | GUAIANE SESQUITERPENE POLYMER AND PREPARATION METHOD THEREFOR AND USE THEREOF | KUNMING INST BOTANY CAS (CN) | 2026-01-28 | — | — | EP | disclosed |
| US-20240409552-A1 | GUAIANOLIDE OLIGOMERS, PREPARATION METHOD AND APPLICATION | KUNMING INSTITUTE OF BOTANY, CHINESE ACADEMY OF SCIENCES (CN) | 2024-12-12 | — | — | US | disclosed |
| EP-4403559-A1 | GUAIANE SESQUITERPENE POLYMER AND PREPARATION METHOD THEREFOR AND USE THEREOF | Kunming Institute of Botany, Chinese Academy of Sciences (CN) | 2024-07-24 | — | — | EP | disclosed |
| CN-113788840-B | Guaiane sesquiterpene polymer and medicine thereof, and preparation method and application thereof | 中国科学院昆明植物研究所 | 2023-08-11 | — | — | CN | disclosed |
| WO-2023040703-A1 | GUAIANE SESQUITERPENE POLYMER AND PREPARATION METHOD THEREFOR AND USE THEREOF | 中国科学院昆明植物研究所 | 2023-03-23 | — | — | WO | disclosed |
| CN-114539195-A | Ludartin derivative, pharmaceutical composition thereof, preparation method and application thereof | 中国科学院昆明植物研究所 | 2022-05-27 | — | — | CN | disclosed |
| CN-114539195-A | Ludartin derivative, pharmaceutical composition thereof, preparation method and application thereof | 中国科学院昆明植物研究所 | 2022-05-27 | — | — | CN | disclosed |
| CN-114539195-A | Ludartin derivative, pharmaceutical composition thereof, preparation method and application thereof | 中国科学院昆明植物研究所 | 2022-05-27 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240409552-A1 | GUAIANOLIDE OLIGOMERS, PREPARATION METHOD AND APPLICATION | HNRNPA2B1, ADM2, GNE | CYP19A1 92/4885PKM 2775/4885NLRP3 3554/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.