Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.52 |
| ▸ | RAB9A | P51151 | 6/20 | 0.52 |
| ▸ | NPC1 | O15118 | 4/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.52 |
| ▸ | HTT | P42858 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.48 |
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | IDH1 | O75874 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.45 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29556819 | 0.97 | MAPT (0.52) | MAPTRAB9ANPC1SMN1; SMN2HTT | |
| SCHEMBL29557053 | 0.90 | RAB9A (0.47) | MAPTRAB9ANPC1SMN1; SMN2HTT | |
| SCHEMBL29556243 | 0.88 | TP53 (0.62) | MAPTRAB9ANPC1SMN1; SMN2HTT | |
| SCHEMBL29556076 | 0.88 | RAB9A (0.68) | MAPTRAB9ANPC1SMN1; SMN2HTT | |
| SCHEMBL29555889 | 0.85 | MAPT (0.56) | MAPTRAB9ANPC1SMN1; SMN2HTT | |
| SCHEMBL29556187 | 0.84 | MEN1 (0.61) | MAPTRAB9AHTTKMT2AMEN1 | |
| SCHEMBL29555610 | 0.84 | MEN1 (0.61) | MAPTRAB9AHTTKMT2AMEN1 | |
| SCHEMBL29556370 | 0.82 | MAPT (0.50) | MAPTRAB9ANPC1SMN1; SMN2HTT | |
| SCHEMBL29556017 | 0.82 | RAB9A (0.48) | MAPTRAB9ANPC1SMN1; SMN2HTT | |
| SCHEMBL23832118 | 0.81 | MAPT (0.44) | MAPTRAB9ANPC1SMN1; SMN2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022078533-A1 | SUBSTITUTED 1,3-DIPHENYLUREA DERIVATIVES AND 1-PHENYL-3-PYRIDYLUREA DERIVATIVES FOR PLANT BIOTECHNOLOGY, PREPARATIONS CONTAINING THESE COMPOUNDS AND USE THEREOF | USTAV EXPERIMENTALNI BOTANIKY AV CR, V.V.I. (CZ) | 2022-04-21 | — | — | WO | disclosed |