Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.62 |
| ▸ | TSHR | P16473 | 1/20 | 0.62 |
| ▸ | RAB9A | P51151 | 8/20 | 0.61 |
| ▸ | MAPT | P10636 | 6/20 | 0.61 |
| ▸ | NPC1 | O15118 | 5/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.61 |
| ▸ | HTT | P42858 | 4/20 | 0.60 |
| ▸ | PKM | P14618 | 1/20 | 0.60 |
| ▸ | CNR1 | P21554 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 3/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.59 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | MITF | O75030 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | STAT1 | P42224 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29556076 | 0.90 | RAB9A (0.68) | TP53TSHRRAB9AMAPTNPC1 | |
| SCHEMBL29556196 | 0.88 | MAPT (0.52) | RAB9AMAPTNPC1SMN1; SMN2HTT | |
| SCHEMBL25002342 | 0.86 | MAPT (0.73) | TP53TSHRRAB9AMAPTNPC1 | |
| SCHEMBL29556819 | 0.85 | MAPT (0.52) | RAB9AMAPTNPC1SMN1; SMN2HTT | |
| SCHEMBL29556252 | 0.84 | RAB9A (0.82) | RAB9AMAPTNPC1HTTCNR1 | |
| SCHEMBL29555917 | 0.84 | MEN1 (0.82) | TP53TSHRRAB9AMAPTNPC1 | |
| SCHEMBL29555874 | 0.83 | MAPT (0.66) | TP53TSHRRAB9AMAPTNPC1 | |
| SCHEMBL29555975 | 0.83 | MAPT (0.68) | TP53TSHRRAB9AMAPTNPC1 | |
| SCHEMBL22103791 | 0.83 | TSHR (0.82) | TP53TSHRRAB9AMAPTNPC1 | |
| SCHEMBL4893387 | 0.83 | TP53 (0.87) | TP53TSHRRAB9AMAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022078533-A1 | SUBSTITUTED 1,3-DIPHENYLUREA DERIVATIVES AND 1-PHENYL-3-PYRIDYLUREA DERIVATIVES FOR PLANT BIOTECHNOLOGY, PREPARATIONS CONTAINING THESE COMPOUNDS AND USE THEREOF | USTAV EXPERIMENTALNI BOTANIKY AV CR, V.V.I. (CZ) | 2022-04-21 | — | — | WO | disclosed |