Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 12/20 | 0.68 |
| ▸ | MEN1 | O00255 | 11/20 | 0.68 |
| ▸ | LMNA | P02545 | 6/20 | 0.68 |
| ▸ | MAPT | P10636 | 5/20 | 0.68 |
| ▸ | HTT | P42858 | 4/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.68 |
| ▸ | RAB9A | P51151 | 8/20 | 0.66 |
| ▸ | NPC1 | O15118 | 7/20 | 0.62 |
| ▸ | POLB | P06746 | 2/20 | 0.62 |
| ▸ | KDR | P35968 | 1/20 | 0.60 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.55 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9410880 | 0.85 | MEN1 (0.72) | KMT2AMEN1LMNAMAPTHTT | |
| SCHEMBL29556176 | 0.85 | RAB9A (0.65) | KMT2AMEN1LMNAMAPTRAB9A | |
| SCHEMBL29556163 | 0.85 | KMT2A (0.72) | KMT2AMEN1LMNAMAPTHTT | |
| SCHEMBL30318910 | 0.84 | TAAR1 (0.61) | KMT2AMEN1LMNAMAPTHTT | |
| SCHEMBL10344917 | 0.84 | TAAR1 (0.61) | KMT2AMEN1LMNAMAPTHTT | |
| SCHEMBL29556285 | 0.84 | MEN1 (0.52) | KMT2AMEN1LMNAMAPTHTT | |
| SCHEMBL22125175 | 0.83 | SMARCA2 (0.71) | KMT2AMEN1LMNAMAPT | |
| SCHEMBL29555820 | 0.82 | KMT2A (0.68) | KMT2AMEN1LMNAMAPTHTT | |
| SCHEMBL2682054 | 0.82 | KMT2A (1.00) | KMT2AMEN1LMNAMAPTHTT | |
| SCHEMBL27583080 | 0.80 | KMT2A (0.74) | KMT2AMEN1LMNAMAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022078533-A1 | SUBSTITUTED 1,3-DIPHENYLUREA DERIVATIVES AND 1-PHENYL-3-PYRIDYLUREA DERIVATIVES FOR PLANT BIOTECHNOLOGY, PREPARATIONS CONTAINING THESE COMPOUNDS AND USE THEREOF | USTAV EXPERIMENTALNI BOTANIKY AV CR, V.V.I. (CZ) | 2022-04-21 | — | — | WO | disclosed |