Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 7/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.52 |
| ▸ | RAB9A | P51151 | 6/20 | 0.52 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | LMNA | P02545 | 4/20 | 0.49 |
| ▸ | SMARCA2 | P51531 | 5/20 | 0.49 |
| ▸ | SMARCA4 | P51532 | 4/20 | 0.49 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | CNR1 | P21554 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.44 |
| ▸ | RELA | Q04206 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29556405 | 0.90 | RAB9A (0.49) | MEN1KMT2ARAB9AMAPTLMNA | |
| SCHEMBL29555838 | 0.89 | SMARCA2 (0.64) | MEN1KMT2ARAB9AMAPTLMNA | |
| SCHEMBL29556206 | 0.86 | MEN1 (0.50) | MEN1KMT2ARAB9AMAPTLMNA | |
| SCHEMBL29556199 | 0.84 | KMT2A (0.68) | MEN1KMT2ARAB9AMAPTLMNA | |
| SCHEMBL29556404 | 0.83 | MEN1 (0.51) | MEN1KMT2ARAB9AMAPTLMNA | |
| SCHEMBL29556287 | 0.83 | CNR1 (0.55) | MEN1KMT2ARAB9AMAPTLMNA | |
| SCHEMBL29556191 | 0.83 | MAPT (0.51) | MEN1KMT2ARAB9AMAPTLMNA | |
| SCHEMBL22125175 | 0.82 | SMARCA2 (0.71) | MEN1KMT2AMAPTLMNASMARCA2 | |
| SCHEMBL29555610 | 0.81 | MEN1 (0.61) | MEN1KMT2ARAB9AMAPTLMNA | |
| SCHEMBL29556187 | 0.81 | MEN1 (0.61) | MEN1KMT2ARAB9AMAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022078533-A1 | SUBSTITUTED 1,3-DIPHENYLUREA DERIVATIVES AND 1-PHENYL-3-PYRIDYLUREA DERIVATIVES FOR PLANT BIOTECHNOLOGY, PREPARATIONS CONTAINING THESE COMPOUNDS AND USE THEREOF | USTAV EXPERIMENTALNI BOTANIKY AV CR, V.V.I. (CZ) | 2022-04-21 | — | — | WO | disclosed |