Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRAF | P15056 | 6/20 | 0.57 |
| ▸ | KDR | P35968 | 6/20 | 0.56 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.53 |
| ▸ | NAMPT | P43490 | 1/20 | 0.51 |
| ▸ | FLT3 | P36888 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | CASP3 | P42574 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29555831 | 0.84 | HDAC3 (0.47) | BRAFKDREPHX2MAPTNPC1 | |
| SCHEMBL29556410 | 0.82 | MTOR (0.61) | BRAFKDREPHX2ALDH1A1MAPT | |
| SCHEMBL4110392 | 0.80 | MAPT (0.64) | EPHX2ALDH1A1MAPTHTTGAA | |
| SCHEMBL29556176 | 0.79 | RAB9A (0.65) | MAPTGAANPC1RAB9AMEN1 | |
| SCHEMBL10344917 | 0.79 | TAAR1 (0.61) | KDREPHX2FLT3MAPTHTT | |
| SCHEMBL30318910 | 0.79 | TAAR1 (0.61) | KDREPHX2FLT3MAPTHTT | |
| SCHEMBL5961454 | 0.79 | EPHX2 (0.57) | BRAFKDREPHX2NAMPTFLT3 | |
| SCHEMBL11195290 | 0.79 | MAPT (0.68) | BRAFKDREPHX2ALDH1A1MAPT | |
| SCHEMBL29555946 | 0.79 | MAPT (0.61) | BRAFKDREPHX2NAMPTFLT3 | |
| SCHEMBL29555891 | 0.79 | P2RX1 (0.67) | EPHX2ALDH1A1MAPTHTTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022078533-A1 | SUBSTITUTED 1,3-DIPHENYLUREA DERIVATIVES AND 1-PHENYL-3-PYRIDYLUREA DERIVATIVES FOR PLANT BIOTECHNOLOGY, PREPARATIONS CONTAINING THESE COMPOUNDS AND USE THEREOF | USTAV EXPERIMENTALNI BOTANIKY AV CR, V.V.I. (CZ) | 2022-04-21 | — | — | WO | disclosed |