Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 7/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.64 |
| ▸ | MAPT | P10636 | 5/20 | 0.64 |
| ▸ | LMNA | P02545 | 4/20 | 0.64 |
| ▸ | HTT | P42858 | 3/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.64 |
| ▸ | GRIK1 | P39086 | 3/20 | 0.60 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.60 |
| ▸ | RAB9A | P51151 | 4/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.60 |
| ▸ | NPC1 | O15118 | 2/20 | 0.58 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | TGM2 | P21980 | 1/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29556215 | 0.95 | MEN1 (0.67) | MEN1KMT2AMAPTLMNAHTT | |
| SCHEMBL29555972 | 0.94 | MEN1 (0.74) | MEN1KMT2AMAPTLMNAHTT | |
| SCHEMBL29556941 | 0.88 | GAA (0.59) | MEN1KMT2AMAPTLMNAHTT | |
| SCHEMBL29555934 | 0.88 | MEN1 (0.58) | MEN1KMT2AMAPTLMNAHTT | |
| SCHEMBL29555992 | 0.86 | MEN1 (0.56) | MEN1KMT2AMAPTLMNAHTT | |
| SCHEMBL29556074 | 0.86 | MAPT (0.61) | MEN1KMT2AMAPTLMNAHTT | |
| SCHEMBL29556248 | 0.86 | MAPT (0.61) | MEN1KMT2AMAPTLMNAHTT | |
| SCHEMBL19707566 | 0.86 | GAA (0.65) | MEN1KMT2AMAPTLMNAHTT | |
| SCHEMBL30995906 | 0.85 | CNR1 (0.67) | MEN1KMT2AMAPTLMNAHTT | |
| SCHEMBL29555591 | 0.83 | MEN1 (0.61) | MEN1KMT2AMAPTLMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022078533-A1 | SUBSTITUTED 1,3-DIPHENYLUREA DERIVATIVES AND 1-PHENYL-3-PYRIDYLUREA DERIVATIVES FOR PLANT BIOTECHNOLOGY, PREPARATIONS CONTAINING THESE COMPOUNDS AND USE THEREOF | USTAV EXPERIMENTALNI BOTANIKY AV CR, V.V.I. (CZ) | 2022-04-21 | — | — | WO | disclosed |