Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.59 |
| ▸ | TGM2 | P21980 | 1/20 | 0.59 |
| ▸ | GRIK1 | P39086 | 3/20 | 0.56 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.56 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.56 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.56 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.54 |
| ▸ | GRM5 | P41594 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | DDX3X | O00571 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | MAOA | P21397 | 1/20 | 0.53 |
| ▸ | MAOB | P27338 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19707566 | 0.94 | GAA (0.65) | GAATGM2GRIK1GRIK2TRPV1 | |
| SCHEMBL29556097 | 0.89 | MAOA (0.69) | GAATGM2GRIK1GRIK2STING1 | |
| SCHEMBL29556788 | 0.88 | MEN1 (0.64) | GAATGM2GRIK1GRIK2MEN1 | |
| SCHEMBL11051606 | 0.87 | MAOA (0.72) | GAATGM2GRIK1GRIK2TRPV1 | |
| SCHEMBL12644777 | 0.86 | MAOA (0.71) | MEN1KMT2AALDH1A1LMNAMAPT | |
| SCHEMBL29556215 | 0.86 | MEN1 (0.67) | GRIK1GRIK2MEN1KMT2AALDH1A1 | |
| SCHEMBL29555929 | 0.86 | RAB9A (0.64) | GAAMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL11003357 | 0.86 | POLB (0.60) | GAATGM2GRIK1GRIK2TRPV1 | |
| SCHEMBL27193045 | 0.85 | MAPK14 (0.54) | MEN1KMT2AALDH1A1LMNAMAPT | |
| SCHEMBL5950029 | 0.84 | GRIK1 (0.57) | GAATGM2GRIK1GRIK2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022078533-A1 | SUBSTITUTED 1,3-DIPHENYLUREA DERIVATIVES AND 1-PHENYL-3-PYRIDYLUREA DERIVATIVES FOR PLANT BIOTECHNOLOGY, PREPARATIONS CONTAINING THESE COMPOUNDS AND USE THEREOF | USTAV EXPERIMENTALNI BOTANIKY AV CR, V.V.I. (CZ) | 2022-04-21 | — | — | WO | disclosed |