Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2B | P29275 | 5/20 | 0.65 |
| ▸ | TNF | P01375 | 4/20 | 0.60 |
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | USP2 | O75604 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.54 |
| ▸ | ACHE | P22303 | 1/20 | 0.54 |
| ▸ | PDE4A | P27815 | 1/20 | 0.54 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.54 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.54 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.54 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29854228 | 0.89 | ADORA2B (0.65) | ADORA2BTNFTSHRLMNAUSP2 | |
| SCHEMBL10394509 | 0.80 | MAPK1 (0.73) | ADORA2BSMN1; SMN2RXFP1MEN1KMT2A | |
| SCHEMBL356160 | 0.79 | ADORA2B (1.00) | ADORA2BTNFTSHRLMNAUSP2 | |
| SCHEMBL9392195 | 0.79 | POLB (0.65) | ADORA2BTNFTSHRLMNAUSP2 | |
| SCHEMBL25248792 | 0.79 | ADORA2B (0.62) | ADORA2BTNFTSHRLMNAUSP2 | |
| Iodide SCHEMBL28480464 | 0.78 | MAPK1 (0.72) | ADORA2BSMN1; SMN2RXFP1MEN1KMT2A | |
| SCHEMBL13659013 | 0.78 | ALDH1A1 (0.53) | ADORA2BTSHRSMN1; SMN2RXFP1ALDH1A1 | |
| SCHEMBL25248989 | 0.78 | ADORA2B (0.68) | ADORA2BTNFTSHRLMNAUSP2 | |
| SCHEMBL8649006 | 0.78 | TNF (0.52) | ADORA2BTNFTSHRLMNAUSP2 | |
| SCHEMBL20863739 | 0.77 | ADORA2B (1.00) | ADORA2BTNFTSHRLMNAUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240094220-A1 | ENGINEERING BACILLUS SUBTILIS AS A VERSATILE AND STABLE PLATFORM FOR PRODUCTION OF NANOBODIES | NORTHEASTERN UNIVERSITY | 2024-03-21 | — | — | US | disclosed |
| EP-4041296-A1 | ENGINEERING BACILLUS SUBTILIS AS A VERSATILE AND STABLE PLATFORM FOR PRODUCTION OF NANOBODIES | Northeastern University (US) | 2022-08-17 | — | — | EP | disclosed |
| CN-111748571-B | Method for engineering bacillus subtilis into multifunctional stable platform for producing nano antibody | 浙江禾霖生物科技有限公司 | 2022-05-03 | — | — | CN | disclosed |