Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.46 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.46 |
| ▸ | PNP | P00491 | 1/20 | 0.43 |
| ▸ | GSK3A | P49840 | 2/20 | 0.42 |
| ▸ | RPS6KA3 | P51812 | 2/20 | 0.42 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | HINT1 | P49773 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 2/20 | 0.40 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.40 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23827894 | 1.00 | KDM4E (0.46) | KDM4ETAS1R3TAS1R1PNPGSK3A | |
| SCHEMBL29558174 | 1.00 | KDM4E (0.46) | KDM4ETAS1R3TAS1R1PNPGSK3A | |
| SCHEMBL29558873 | 0.94 | TAS1R3 (0.45) | KDM4ETAS1R3TAS1R1PNPGSK3A | |
| SCHEMBL29558193 | 0.94 | TAS1R3 (0.45) | KDM4ETAS1R3TAS1R1PNPGSK3A | |
| SCHEMBL29558256 | 0.94 | TAS1R3 (0.45) | KDM4ETAS1R3TAS1R1PNPGSK3A | |
| SCHEMBL29557884 | 0.92 | TAS1R3 (0.43) | KDM4ETAS1R3TAS1R1PNPGSK3A | |
| SCHEMBL28790125 | 0.91 | TAS1R3 (0.43) | KDM4ETAS1R3TAS1R1PNPGSK3A | |
| SCHEMBL29557705 | 0.91 | TAS1R3 (0.44) | KDM4ETAS1R3TAS1R1PNPGSK3A | |
| SCHEMBL29557782 | 0.91 | TAS1R3 (0.44) | KDM4ETAS1R3TAS1R1PNPGSK3A | |
| SCHEMBL12582835 | 0.89 | MEN1 (0.51) | KDM4ETAS1R3TAS1R1PNPGSK3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3999118-A1 | ANTIBODY-STING AGONIST CONJUGATES AND THEIR USE IN IMMUNOTHERAPY | Immunesensor Therapeutics, Inc. (US) | 2022-05-25 | — | — | EP | disclosed |