SCHEMBL23827894

SCHEMBL23827894

CC(=O)O[C@@H]1[C@H](CCO)[C@@H](COC(=O)c2ccccc2)O[C@H]1n1cnc2c(=O)[nH]c(NC(=O)C(C)C)nc21

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KDM4E B2RXH2 1/20 0.46
▸ TAS1R3 Q7RTX0 2/20 0.46
▸ TAS1R1 Q7RTX1 2/20 0.46
▸ PNP P00491 1/20 0.43
▸ GSK3A P49840 2/20 0.42
▸ RPS6KA3 P51812 2/20 0.42
▸ MAPK14 Q16539 2/20 0.42
▸ ALDH1A1 P00352 2/20 0.42
▸ LMNA P02545 2/20 0.42
▸ TP53 P04637 1/20 0.42
▸ MAPT P10636 1/20 0.42
▸ TDP1 Q9NUW8 1/20 0.42
▸ HINT1 P49773 1/20 0.41
▸ MEN1 O00255 2/20 0.41
▸ KMT2A Q03164 2/20 0.41
▸ USP2 O75604 1/20 0.41
▸ POLB P06746 1/20 0.41
▸ ACHE P22303 2/20 0.40
▸ PRKAB2 O43741 1/20 0.40
▸ PRKAG1 P54619 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29558174 1.00 KDM4E (0.46) KDM4ETAS1R3TAS1R1PNPGSK3A
SCHEMBL29557868 1.00 KDM4E (0.46) KDM4ETAS1R3TAS1R1PNPGSK3A
SCHEMBL29558873 0.94 TAS1R3 (0.45) KDM4ETAS1R3TAS1R1PNPGSK3A
SCHEMBL29558193 0.94 TAS1R3 (0.45) KDM4ETAS1R3TAS1R1PNPGSK3A
SCHEMBL29558256 0.94 TAS1R3 (0.45) KDM4ETAS1R3TAS1R1PNPGSK3A
SCHEMBL29557884 0.92 TAS1R3 (0.43) KDM4ETAS1R3TAS1R1PNPGSK3A
SCHEMBL28790125 0.91 TAS1R3 (0.43) KDM4ETAS1R3TAS1R1PNPGSK3A
SCHEMBL29557705 0.91 TAS1R3 (0.44) KDM4ETAS1R3TAS1R1PNPGSK3A
SCHEMBL29557782 0.91 TAS1R3 (0.44) KDM4ETAS1R3TAS1R1PNPGSK3A
SCHEMBL12582835 0.89 MEN1 (0.51) KDM4ETAS1R3TAS1R1PNPGSK3A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12311030-B2 Antibody-sting agonist conjugates and their use in immunotherapy IMMUNESENSOR THERAPEUTICS, INC. (US) 2025-05-27 — — US disclosed
CN-114786729-A antibody-STING agonist conjugates and their use in immunotherapy 免疫传感器治疗股份有限公司 2022-07-22 — — CN disclosed
EP-3999118-A1 ANTIBODY-STING AGONIST CONJUGATES AND THEIR USE IN IMMUNOTHERAPY Immunesensor Therapeutics, Inc. (US) 2022-05-25 — — EP disclosed
US-20220105198-A1 ANTIBODY-STING AGONIST CONJUGATES AND THEIR USE IN IMMUNOTHERAPY IMMUNESENSOR THERAPEUTICS, INC. 2022-04-07 — — US disclosed
US-11213592-B2 Antibody-sting agonist conjugates and their use in immunotherapy IMMUNESENSOR THERAPEUTICS, INC. (US) 2022-01-04 — — US disclosed
US-20210290774-A1 ANTIBODY-STING AGONIST CONJUGATES AND THEIR USE IN IMMUNOTHERAPY IMMUNESENSOR THERAPEUTICS, INC. (US) 2021-09-23 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11213592-B2 Antibody-sting agonist conjugates and their use in immunotherapy STING1, CGAS, MAVS KDM4E 3364/4885TAS1R3 1716/4885TAS1R1 1483/4885
US-20210290774-A1 ANTIBODY-STING AGONIST CONJUGATES AND THEIR USE IN IMMUNOTHERAPY STING1, CGAS, MAVS KDM4E 3364/4885TAS1R3 1716/4885TAS1R1 1483/4885
US-20220105198-A1 ANTIBODY-STING AGONIST CONJUGATES AND THEIR USE IN IMMUNOTHERAPY STING1, CGAS, MAVS KDM4E 3364/4885TAS1R3 1716/4885TAS1R1 1483/4885
US-12311030-B2 Antibody-sting agonist conjugates and their use in immunotherapy STING1, CGAS, MAVS KDM4E 3364/4885TAS1R3 1716/4885TAS1R1 1483/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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