Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACP3 | P15309 | 1/20 | 0.45 |
| ▸ | CNR2 | P34972 | 2/20 | 0.44 |
| ▸ | IDO1 | P14902 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | TDO2 | P48775 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.37 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.37 |
| ▸ | CACNB1 | Q02641 | 1/20 | 0.37 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.37 |
| ▸ | MC4R | P32245 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10216843 | 1.00 | ACP3 (0.45) | ACP3CNR2IDO1ALDH1A1POLB | |
| Hydrochloric Acid SCHEMBL382176 | 0.98 | ACP3 (0.44) | ACP3CNR2IDO1ALDH1A1POLB | |
| SCHEMBL19265315 | 0.85 | ACP3 (0.42) | ACP3CNR2IDO1ALDH1A1POLB | |
| SCHEMBL10216941 | 0.85 | ACP3 (0.42) | ACP3CNR2IDO1ALDH1A1POLB | |
| SCHEMBL17818994 | 0.84 | P2RX7 (0.54) | ACP3CNR2IDO1TDO2P2RX7 | |
| Hydrochloric Acid SCHEMBL409850 | 0.83 | ACP3 (0.41) | ACP3CNR2IDO1ALDH1A1POLB | |
| SCHEMBL10591850 | 0.82 | ALDH1A1 (0.42) | ALDH1A1POLBTDP1GAAGRIN2D | |
| SCHEMBL11662073 | 0.82 | HTR2C (0.42) | ACP3CNR2IDO1ALDH1A1POLB | |
| SCHEMBL8396680 | 0.82 | ACP3 (0.46) | ACP3CNR2IDO1ALDH1A1POLB | |
| SCHEMBL1729214 | 0.80 | MC4R (0.42) | ACP3CNR2IDO1ALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114057765-A | 3-aryl-4-amido-bicyclo [4,5,0] hydroxamic acids as HDAC inhibitors | 瓦洛健康股份有限公司 | 2022-02-18 | — | — | CN | disclosed |