Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD1 | P21728 | 14/20 | 0.76 |
| ▸ | DRD2 | P14416 | 8/20 | 0.76 |
| ▸ | DRD5 | P21918 | 4/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.60 |
| ▸ | HPGD | P15428 | 3/20 | 0.60 |
| ▸ | MAPT | P10636 | 2/20 | 0.60 |
| ▸ | ADCY5 | O95622 | 2/20 | 0.60 |
| ▸ | ADCY6 | O43306 | 1/20 | 0.60 |
| ▸ | ADCY3 | O60266 | 1/20 | 0.60 |
| ▸ | ADCY9 | O60503 | 1/20 | 0.60 |
| ▸ | ADCY8 | P40145 | 1/20 | 0.60 |
| ▸ | ADCY7 | P51828 | 1/20 | 0.60 |
| ▸ | ADCY2 | Q08462 | 1/20 | 0.60 |
| ▸ | ADCY1 | Q08828 | 1/20 | 0.60 |
| ▸ | ADCY4 | Q8NFM4 | 1/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.60 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.60 |
| ▸ | THPO | P40225 | 1/20 | 0.60 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL10690789 | 0.99 | DRD1 (0.74) | DRD1DRD2DRD5KDM4EHPGD | |
| SCHEMBL13007204 | 0.86 | DRD1 (1.00) | DRD1DRD2DRD5KDM4EHPGD | |
| SCHEMBL10692914 | 0.83 | HTR2A (0.59) | DRD1DRD2DRD5KDM4EHPGD | |
| SCHEMBL10693955 | 0.82 | DRD1 (0.70) | DRD1DRD2DRD5KDM4EHPGD | |
| Hydrochloric Acid SCHEMBL10692816 | 0.82 | HTR2A (0.58) | DRD1DRD2DRD5KDM4EHPGD | |
| Bromide SCHEMBL10689985 | 0.81 | DRD1 (0.70) | DRD1DRD2DRD5KDM4EHPGD | |
| SCHEMBL10687457 | 0.81 | DRD1 (0.68) | DRD1DRD2DRD5KDM4EHPGD | |
| SCHEMBL13901044 | 0.79 | DRD1 (0.72) | DRD1DRD2DRD5KDM4EHPGD | |
| SCHEMBL10690380 | 0.78 | DRD1 (0.71) | DRD1DRD2DRD5KDM4EHPGD | |
| Bromide SCHEMBL10691988 | 0.77 | DRD1 (0.72) | DRD1DRD2DRD5KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4706758-A2 | METHODS FOR INHIBITING PHOSPHATE TRANSPORT | Ardelyx, Inc. (US) | 2026-03-11 | — | — | EP | disclosed |
| US-20240325487-A1 | COMPOUNDS AND METHODS FOR INHIBITING PHOSPHATE TRANSPORT | ARDELYX, INC. | 2024-10-03 | — | — | US | disclosed |
| US-11813304-B2 | Compounds and methods for inhibiting phosphate transport | ARDELYX, INC. (US) | 2023-11-14 | — | — | US | disclosed |
| US-20230277523-A1 | METHODS FOR INHIBITING PHOSPHATE TRANSPORT | ARDELYX, INC. (US) | 2023-09-07 | — | — | US | disclosed |
| EP-3884935-B1 | COMPOUNDS AND METHODS FOR INHIBITING PHOSPHATE TRANSPORT | ARDELYX INC (US) | 2023-06-14 | — | — | EP | disclosed |
| CN-114404588-A | Compounds and methods for inhibiting phosphate transport | 阿德利克斯公司 | 2022-04-29 | — | — | CN | disclosed |
| CN-114340631-A | Combination for reducing serum phosphate in a patient | 阿德利克斯股份有限公司 | 2022-04-12 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240325487-A1 | COMPOUNDS AND METHODS FOR INHIBITING PHOSPHATE TRANSPORT | SLC34A3, SLC34A2, SLC34A1 | DRD1 4625/4885DRD2 4720/4885DRD5 4201/4885 |
| US-11813304-B2 | Compounds and methods for inhibiting phosphate transport | SLC34A3, SLC34A2, SLC34A1 | DRD1 4625/4885DRD2 4720/4885DRD5 4201/4885 |
| US-20230277523-A1 | METHODS FOR INHIBITING PHOSPHATE TRANSPORT | SLC34A3, SLC34A2, SLC34A1 | DRD1 4870/4885DRD2 4876/4885DRD5 4655/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.